SCHEMBL3483705

SCHEMBL3483705

CS(=O)(=O)Cc1ccccc1SS

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
GAA P10253 1/20 0.35
ALOX15 P16050 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
OPRL1 P41146 3/20 0.33
OPRM1 P35372 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
APOBEC3G Q9HC16 1/20 0.32
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
FFAR1 O14842 1/20 0.32
NQO2 P16083 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL943394 0.84 APOBEC3G (0.48) LMNAGAAALOX15TDP1OPRL1
SCHEMBL513976 0.82 SLC6A2 (0.43) LMNAGAASLC6A2SLC6A4SLC6A3
SCHEMBL3483641 0.78 PSIP1 (0.44) LMNA
SCHEMBL775854 0.77 GABRA1 (0.41) LMNAAPOBEC3GSLC6A2SLC6A4
SCHEMBL9256894 0.73 GABRA1 (0.41) LMNAGAAALOX15TDP1CA1
SCHEMBL2376651 0.71 ALDH1A1 (0.49) LMNAGAACA2
SCHEMBL2634762 0.71 GAA (0.43) LMNAGAAALOX15TDP1OPRL1
SCHEMBL30659891 0.71 GAA (0.43) LMNAGAAALOX15TDP1OPRL1
SCHEMBL23004816 0.69 PNMT (0.41) LMNAGAAALOX15TDP1CA1
SCHEMBL647765 0.69 ALDH1A1 (0.39) LMNAGAAALOX15TDP1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7851646-B2 formed by reacting aryl sulfur compound with halogen and fluoro salt to form arylsulfur halotetrafluoride which is reacted with fluoride source to form target arylsulfur pentafluoride; for production of fungicides, herbicides, and insecticides IM&T RESEARCH, INC. (US) 2010-12-14 US disclosed
US-20100076215-A9 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-03-25 US disclosed
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA LMNA 4733/4885GAA 1978/4885ALOX15 3399/4885
US-20100076215-A9 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA LMNA 4733/4885GAA 1978/4885ALOX15 3399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.