SCHEMBL348409

SCHEMBL348409

CC(C)(C)c1ccc(-c2ccccc2)c(P)c1C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ESR2 Q92731 1/20 0.32
PLAU P00749 1/20 0.31
ALOX5 P09917 1/20 0.31
ALOX5AP P20292 2/20 0.30
FEN1 P39748 2/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30135690 1.00 ALDH1A1 (0.32) ALDH1A1TSHRTDP1ESR2PLAU
SCHEMBL2548208 0.85 ALDH1A1 (0.32) ALDH1A1TSHRTDP1ESR2PLAU
SCHEMBL28506719 0.82 ALDH1A1 (0.35) ALDH1A1TSHRTDP1ESR2PLAU
SCHEMBL9960735 0.79 GABRA1 (0.35) ALDH1A1TSHRTDP1
SCHEMBL25258472 0.78 FEN1 (0.40) ALDH1A1TSHRTDP1ESR2ALOX5AP
SCHEMBL18074251 0.78 ALDH1A1 (0.32) ALDH1A1TSHRTDP1ESR2PLAU
SCHEMBL28882059 0.78 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ESR2PLAU
SCHEMBL6677589 0.78 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ESR2PLAU
SCHEMBL28099521 0.77 DPP4 (0.33)
SCHEMBL3692332 0.77 CA2 (0.40) ALDH1A1TSHRTDP1CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2139838-B1 A PROCESS FOR THE PREPARATION OF 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTOIC ACID GRINDEKS JSC (LV) 2012-03-28 EP claimed
US-20100160677-A1 PROCESS FOR PREPARATION OF 6-[3-(1-ADMANTYL)-4-METHOXYPHENYL]-2-NAPHTOIC ACID. JSC GRINDEKS (LV) 2010-06-24 US claimed
US-20050026059-A1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus TANAKA TAKAKAZU (JP) 2005-02-03 US claimed
US-6818368-B2 AN ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER INCLUDES CHARGE GENERATING AND CHARGE TRANSFER MATERIALS, CHARGE TRANSFER MATERIAL CONTAINS A TRIARYLAMINE COMPOUND FORMED FROM AN AMINE AND AN ARYLHALIDE WITH PHOSPHINE COMOUND CATALYST CANON KABUSHIKI KAISHA (JP) 2004-11-16 US claimed
US-20020048710-A1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2002-04-25 US claimed
EP-3569606-B1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORP (US) 2022-01-05 EP disclosed
US-10978649-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-13 US disclosed
US-10870715-B2 Solid polyaluminoxane composition, olefin polymerization catalyst, olefin polymer production method and solid polyaluminoxane composition production method MITSUI CHEMICALS, INC. (JP) 2020-12-22 US disclosed
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-05 US disclosed
US-10749121-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-08-18 US disclosed
EP-3569606-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF Universal Display Corporation (US) 2019-11-20 EP disclosed
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-11-07 US disclosed
WO-2003084972-A1 RHODIUM COMPLEXES AND IRIDIUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2003-10-16 WO disclosed
WO-2003080586-A1 N-SULFONYLUREA APOPTOSIS PROMOTERS ABBOTT LABORATORIES (US) 2003-10-02 WO disclosed
WO-2003077918-A1 DI-ARYL SUBSTITUTED TETRAZOLE MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5 MERCK & CO., INC. (US) 2003-09-25 WO disclosed
US-20030166650-A1 Cinnamide derivatives as KCNQ potassium channel modulators BRISTOL-MYERS SQUIBB COMPANY 2003-09-04 US disclosed
WO-2003062215-A1 4(HETERO-) ARYL SUBSTITUTED (THIA-/OXA-/PYRA) ZOLES FOR INHIBITION OF TIE-2 KYLIX PHARMACEUTICALS B.V. (NL) 2003-07-31 WO disclosed
WO-2003033476-A1 PYRIMIDINONES AS MELANIN CONCENTRATING HORMONE RECEPTOR 1 SMITHKLINE BEECHAM PLC (GB) 2003-04-24 WO disclosed
WO-2002096858-A1 CINNAMIDE DERIVATIVES AS KCNQ POTASSIUM CHANNEL MODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2002-12-05 WO disclosed
US-20020048710-A1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2002-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIG1, L1CAM, LIG3 ALDH1A1 228/4885TSHR 4334/4885TDP1 1904/4885
US-20030166650-A1 Cinnamide derivatives as KCNQ potassium channel modulators KCNH2, KCNH3, KCNQ1 ALDH1A1 2914/4885TSHR 2004/4885TDP1 4537/4885
US-10978649-B2 Organic electroluminescent materials and devices NR2C2, NR2E3, NCOA2 ALDH1A1 2343/4885TSHR 2350/4885TDP1 4371/4885
US-10749121-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 ALDH1A1 228/4885TSHR 4334/4885TDP1 1904/4885
US-20100160677-A1 PROCESS FOR PREPARATION OF 6-[3-(1-ADMANTYL)-4-METHOXYPHENYL]-2-NAPHTOIC ACID. ME1, CD274, PDCD1LG2 ALDH1A1 257/4885TSHR 1065/4885TDP1 2099/4885
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR2C2, NR2E3, NCOA2 ALDH1A1 2343/4885TSHR 2350/4885TDP1 4371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.