Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646869 | 0.83 | GABRA1 (0.39) | GABRA1GABRB2 | |
| SCHEMBL348409 | 0.79 | ALDH1A1 (0.32) | TSHRALDH1A1TDP1 | |
| SCHEMBL30135690 | 0.79 | ALDH1A1 (0.32) | TSHRALDH1A1TDP1 | |
| SCHEMBL4748717 | 0.77 | GABRA1 (0.42) | GABRA1GABRB2HPGDNPC1CASP3 | |
| SCHEMBL20034068 | 0.73 | GABRA1 (0.50) | GABRA1GABRB2HPGDNPC1CASP3 | |
| SCHEMBL30317398 | 0.72 | TSHR (0.45) | HPGDNPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL4748714 | 0.69 | GABRA1 (0.40) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| SCHEMBL10177352 | 0.68 | TSHR (0.45) | HPGDNPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL2548208 | 0.68 | ALDH1A1 (0.32) | TSHRALDH1A1TDP1 | |
| SCHEMBL20780625 | 0.67 | GABRA1 (0.34) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352376-B2 | Catalysts | BOREALIS AG (AT) | 2022-06-07 | — | — | US | disclosed |
| EP-3541823-B1 | CATALYSTS | BOREALIS AG (AT) | 2020-12-30 | — | — | EP | disclosed |
| US-20190308995-A1 | CATALYSTS | BOREALIS AG (AT) | 2019-10-10 | — | — | US | disclosed |
| EP-3541823-A1 | CATALYSTS | Borealis AG (AT) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018091684-A1 | CATALYSTS | BOREALIS AG (AT) | 2018-05-24 | — | — | WO | disclosed |
| CN-105992787-A | Organic semiconductor material | 东洋纺株式会社 | 2016-10-05 | — | — | CN | disclosed |
| EP-2657285-B1 | moulded polypropylene with high content of beta form | BOREALIS AG (AT) | 2015-07-22 | — | — | EP | disclosed |
| US-9079985-B2 | Bridged metallocene catalysts | BOREALIS AG (AT) | 2015-07-14 | — | — | US | disclosed |
| US-20140018506-A1 | BRIDGED METALLOCENE CATALYSTS | BOREALIS AG (AT) | 2014-01-16 | — | — | US | disclosed |
| EP-2655431-A1 | BRIDGED METALLOCENE CATALYSTS | Borealis AG (AT) | 2013-10-30 | — | — | EP | disclosed |
| EP-2657285-A1 | Moulded polypropylene with high content of beta form | Borealis AG (AT) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012084961-A1 | BRIDGED METALLOCENE CATALYSTS | BOREALIS AG (AT) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352376-B2 | Catalysts | SIGMAR1, H1-2, SFN | GABRA1 3084/4885GABRB2 3318/4885HPGD 2849/4885 |
| US-20190308995-A1 | CATALYSTS | SIGMAR1, H1-2, CBR1 | GABRA1 2980/4885GABRB2 3272/4885HPGD 2659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.