Phosphoric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRB1 ADRB2 ADRB3 CYP11B1 DPP4 FGFR1 FGFR2 FGFR3 FGFR4 HRH1 JAK1 JAK2 JAK3 KCNA1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 KDR KIT NA OPRD1 OPRK1 OPRM1 P PDGFRB PIK3CD SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SMO TYK2 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	KMO	O15229	1/20	0.49

▸	POLB	P06746	3/20	0.46

▸	MAPK1	P28482	1/20	0.46

▸	ATM	Q13315	1/20	0.46

▸	ALDH1A1	P00352	4/20	0.43

▸	GLA	P06280	2/20	0.40

▸	THRB	P10828	1/20	0.40

▸	MEN1	O00255	1/20	0.39

▸	KMT2A	Q03164	1/20	0.39

▸	KDM4E	B2RXH2	2/20	0.39

▸	GAA	P10253	2/20	0.39

▸	NPC1	O15118	1/20	0.39

▸	CYP1A2	P05177	1/20	0.39

▸	CYP2C9	P11712	1/20	0.39

▸	CYP2C19	P33261	1/20	0.39

▸	RAB9A	P51151	1/20	0.39

▸	SMN1; SMN2	Q16637	1/20	0.39

▸	CUL4A	Q13619	1/20	0.39

▸	PKM	P14618	1/20	0.38

▸	F12	P00748	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL83509	0.91	POLB (0.53)	KMOPOLBMAPK1ATMALDH1A1
Water SCHEMBL22636774	0.90	POLB (0.52)	KMOPOLBMAPK1ATMALDH1A1
SCHEMBL27741052	0.83	POLB (0.46)	KMOPOLBMAPK1ATMALDH1A1
Pyrrole SCHEMBL25279873	0.81	KMO (0.50)	KMOPOLBMAPK1ATMALDH1A1
SCHEMBL3676899	0.77	PKM (0.56)	KMOPOLBMAPK1ATMMEN1
SCHEMBL3278710	0.77	PKM (0.56)	KMOPOLBMAPK1ATMMEN1
SCHEMBL3485169	0.76	KMT2A (0.47)	KMOPOLBALDH1A1GLATHRB
Phosphoric Acid SCHEMBL3485078	0.75	POLB (0.81)	POLBMAPK1ATMALDH1A1KMT2A
SCHEMBL537817	0.73	KMO (0.51)	KMOPOLBALDH1A1GLATHRB
SCHEMBL6258585	0.71	KDM4E (0.50)	KMOPOLBMAPK1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20100029008-A1	POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES	FEBIT BIOTECH GMBH (DE)	2010-02-04	—	—	US	claimed
US-20100029008-A1	POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES	FEBIT BIOTECH GMBH (DE)	2010-02-04	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20100029008-A1	POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES	POLB, POLM, POLN	KMO 2725/4885POLB 1/4885MAPK1 3105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.