Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.51 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25280975 | 0.78 | KMO (0.49) | KMOCUL4AGLATHRBSLC9A1 | |
| SCHEMBL29373587 | 0.76 | POLB (0.53) | KMOCUL4AGLATHRBSLC9A1 | |
| SCHEMBL83509 | 0.76 | POLB (0.53) | KMOCUL4AGLATHRBSLC9A1 | |
| SCHEMBL14477426 | 0.76 | ALDH1A1 (0.53) | KMOCUL4AGLATHRBSLC9A1 | |
| SCHEMBL14476937 | 0.76 | KEAP1 (0.53) | KMOCUL4ASLC9A1KMT2AMEN1 | |
| Water SCHEMBL2477026 | 0.74 | POLB (0.52) | KMOCUL4AGLATHRBSLC9A1 | |
| Hydrochloric Acid SCHEMBL30439745 | 0.74 | POLB (0.52) | KMOCUL4AGLATHRBSLC9A1 | |
| Water SCHEMBL22636774 | 0.74 | POLB (0.52) | KMOCUL4AGLATHRBSLC9A1 | |
| SCHEMBL27380658 | 0.74 | KMO (0.57) | KMOCUL4AGLATHRBSLC9A1 | |
| SCHEMBL27476986 | 0.72 | KMT2A (0.52) | KMOCUL4AGLATHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242507-A | Sulfonic acid esters | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-12-30 | — | — | US | claimed |
| US-8716435-B2 | Multibranched polyoxyalkylene compound and producing method thereof | NOF CORPORATION (JP) | 2014-05-06 | — | — | US | disclosed |
| EP-2415800-B1 | HYPERBRANCHED POLYOXYALKYLENE COMPOUND AND METHOD FOR PRODUCING SAME | NOF CORP (JP) | 2013-10-16 | — | — | EP | disclosed |
| US-20120225937-A1 | CRYSTALLINE FORMS AND PROCESSES FOR THE PREPARATION OF PG12 RECEPTOR AGONISTS | ARENA PHARMACEUTICALS, INC. (US) | 2012-09-06 | — | — | US | disclosed |
| EP-2480526-A1 | CRYSTALLINE FORMS AND PROCESSES FOR THE PREPARATION OF PGI2 RECEPTOR AGONISTS | Arena Pharmaceuticals, Inc. (US) | 2012-08-01 | — | — | EP | disclosed |
| EP-2415800-A1 | HYPERBRANCHED POLYOXYALKYLENE COMPOUND AND METHOD FOR PRODUCING SAME | NOF Corporation (JP) | 2012-02-08 | — | — | EP | disclosed |
| WO-2011037613-A1 | CRYSTALLINE FORMS AND PROCESSES FOR THE PREPARATION OF PGI2 RECEPTOR AGONISTS | ARENA PHARMACEUTICALS, INC. (US) | 2011-03-31 | — | — | WO | disclosed |
| US-20100261863-A1 | MULTIBRANCHED POLYOXYALKYLENE COMPOUND AND PRODUCING METHOD THEREOF | NOF CORPORATION (JP) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225937-A1 | CRYSTALLINE FORMS AND PROCESSES FOR THE PREPARATION OF PG12 RECEPTOR AGONISTS | PTGIR, PTGIS, TBXA2R | KMO 1397/4885CUL4A 4832/4885GLA 2505/4885 |
| US-20100261863-A1 | MULTIBRANCHED POLYOXYALKYLENE COMPOUND AND PRODUCING METHOD THEREOF | OPRM1, AOC2, OPRK1 | KMO 717/4885CUL4A 2358/4885GLA 3279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.