Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3490267 | 1.00 | CYP3A4 (0.47) | CYP3A4MEN1TSHRKMT2ATP53 | |
| SCHEMBL3490280 | 0.94 | NR3C1 (0.42) | CYP3A4MEN1TSHRKMT2ATP53 | |
| SCHEMBL3490788 | 0.88 | CA1 (0.45) | CYP3A4TDP1LMNARECQLNR3C1 | |
| SCHEMBL3489281 | 0.82 | NR3C1 (0.46) | CYP3A4MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL9218655 | 0.81 | ALDH1A1 (0.54) | CYP3A4MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL9220298 | 0.80 | ALDH1A1 (0.44) | CYP3A4MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL625386 | 0.79 | CYP3A4 (0.54) | CYP3A4MEN1TSHRKMT2ATP53 | |
| SCHEMBL3489037 | 0.79 | L3MBTL1 (0.41) | CYP3A4MEN1KMT2ATP53TDP1 | |
| SCHEMBL9213741 | 0.79 | ALDH1A1 (0.53) | CYP3A4MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL9215811 | 0.78 | NR3C1 (0.44) | CYP3A4MEN1KMT2ATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035866-A1 | NOVEL SUBSTITUTED-1, 1-DIOXO-BENZO[1,2,4]THIADIAZIN-3ONES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035866-A1 | NOVEL SUBSTITUTED-1, 1-DIOXO-BENZO[1,2,4]THIADIAZIN-3ONES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | OPRD1, HTR6, HTR1D | CYP3A4 287/4885MEN1 4200/4885TSHR 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.