Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 14/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 10/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405462 | 0.85 | ALDH1A1 (0.40) | PTGER4PTGER2LMNA | |
| SCHEMBL13311972 | 0.84 | PTGER4 (0.42) | PTGER4PTGER2LMNA | |
| SCHEMBL13348218 | 0.82 | PTGER4 (0.36) | PTGER4PTGER2MAOB | |
| SCHEMBL3502251 | 0.75 | NLRP3 (0.36) | PTGER4PTGER2 | |
| SCHEMBL3502256 | 0.75 | NLRP3 (0.36) | PTGER4PTGER2 | |
| SCHEMBL13312094 | 0.72 | FFAR1 (0.52) | PTGER4PTGER2 | |
| SCHEMBL13312089 | 0.70 | FFAR1 (0.51) | PTGER4PTGER2 | |
| SCHEMBL13348226 | 0.69 | PTGER4 (0.41) | PTGER4PTGER2 | |
| SCHEMBL13311887 | 0.69 | PTGER4 (0.41) | PTGER4PTGER2 | |
| SCHEMBL13312093 | 0.65 | FFAR1 (0.51) | PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | PTGER4 1432/4885PTGER2 3346/4885LMNA 4747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.