Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16828649 | 1.00 | RIPK1 (0.31) | RIPK1LMNA | |
| SCHEMBL757776 | 1.00 | RIPK1 (0.31) | RIPK1LMNA | |
| SCHEMBL17165589 | 1.00 | RIPK1 (0.31) | RIPK1LMNA | |
| SCHEMBL16828725 | 1.00 | RIPK1 (0.31) | RIPK1LMNA | |
| SCHEMBL17165591 | 1.00 | RIPK1 (0.31) | RIPK1LMNA | |
| SCHEMBL25339254 | 1.00 | RIPK1 (0.31) | RIPK1LMNA | |
| SCHEMBL16828603 | 1.00 | RIPK1 (0.31) | RIPK1LMNA | |
| SCHEMBL345737 | 0.85 | RIPK1 (0.34) | RIPK1LMNA | |
| SCHEMBL336027 | 0.85 | RIPK1 (0.34) | RIPK1LMNA | |
| SCHEMBL1098205 | 0.85 | RIPK1 (0.34) | RIPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072427-A1 | GPR 119 MODULATORS | PFIZER INC. | 2013-03-21 | — | — | US | disclosed |
| US-20120295845-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | PFIZER INC | 2012-11-22 | — | — | US | disclosed |
| US-20100285145-A1 | GPR 119 MODULATORS | PFIZER INC | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072427-A1 | GPR 119 MODULATORS | GPR119, GPR65, GPR39 | RIPK1 3001/4885LMNA 3958/4885 |
| US-20100285145-A1 | GPR 119 MODULATORS | GPR119, GPR65, GPR39 | RIPK1 3001/4885LMNA 3958/4885 |
| US-20120295845-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | GPR3, GPR119, GPR84 | RIPK1 3447/4885LMNA 3214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.