SCHEMBL3515213

SCHEMBL3515213

CCCCCC(=O)c1c(O)c(Cl)c(OC)c(Cl)c1O

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
PAK1 Q13153 1/20 0.63
PLA2G2A P14555 2/20 0.54
PLA2G5 P39877 2/20 0.54
FFAR1 O14842 1/20 0.49
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
HTT P42858 2/20 0.45
ATM Q13315 1/20 0.45
TRPV1 Q8NER1 4/20 0.41
HSD17B3 P37058 6/20 0.40
DNMT1 P26358 1/20 0.39
ELANE P08246 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13002136 0.98 MEN1 (0.62) MEN1KMT2APAK1PLA2G2APLA2G5
SCHEMBL13002135 0.98 MEN1 (0.62) MEN1KMT2APAK1PLA2G2APLA2G5
SCHEMBL3516120 0.95 MEN1 (0.57) MEN1KMT2APAK1PLA2G2APLA2G5
SCHEMBL6468921 0.91 MEN1 (0.60) MEN1KMT2APAK1PLA2G2APLA2G5
SCHEMBL13002137 0.88 MEN1 (0.49) MEN1KMT2APAK1PLA2G2APLA2G5
SCHEMBL13002128 0.86 MEN1 (0.55) MEN1KMT2APAK1PLA2G2APLA2G5
SCHEMBL14089180 0.85 MEN1 (0.52) MEN1KMT2APAK1PLA2G2APLA2G5
SCHEMBL13002131 0.84 MEN1 (0.57) MEN1KMT2APAK1PLA2G2APLA2G5
SCHEMBL13002138 0.81 PLA2G2A (0.54) MEN1KMT2APAK1PLA2G2APLA2G5
SCHEMBL13002140 0.81 PLA2G2A (0.54) MEN1KMT2APAK1PLA2G2APLA2G5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698517-A1 <SUP2/>? <SUB2/>?4?NOVEL COMPOUNDS AS ?? <NS1:SUB>7</NS1:SUB>?INHIBITORS Evotec International GmbH (DE) 2026-02-25 EP claimed
US-20260002121-A1 IMPROVED METHODS OF PREPARING DIFFERENT MESODERM CELL TYPES CHILDRENS HOSPITAL MED CT (US) 2026-01-01 US claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 WO claimed
WO-2024218058-A1 NOVEL COMPOUNDS AS α4β7 INHIBITORS EVOTEC INTERNATIONAL GMBH (DE) 2024-10-24 WO claimed
EP-4440586-A1 IMPROVED METHODS OF PREPARING DIFFERENT MESODERM CELL TYPES Children's Hospital Medical Center (US) 2024-10-09 EP claimed
WO-2023102133-A1 IMPROVED METHODS OF PREPARING DIFFERENT MESODERM CELL TYPES CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2023-06-08 WO claimed
US-20220275341-A1 ORGANOID MESODERM LINEAGE DIVERSIFICATION CHILDRENS HOSPITAL MED CT (US) 2022-09-01 US claimed
EP-4022036-A2 ORGANOID MESODERM LINEAGE DIVERSIFICATION Children's Hospital Medical Center, Center for Technology Commercialization (US) 2022-07-06 EP claimed
CN-114430774-A Organoid mesoderm lineage diversification 儿童医院医学中心 2022-05-03 CN claimed
EP-4713433-A2 LIVER ORGANOIDS WITH INTRAHEPATIC SYMPATHETIC NERVES, AND METHODS OF USE THEREOF Children's Hospital Medical Center (US) 2026-03-25 EP disclosed
EP-4698517-A1 <SUP2/>? <SUB2/>?4?NOVEL COMPOUNDS AS ?? <NS1:SUB>7</NS1:SUB>?INHIBITORS Evotec International GmbH (DE) 2026-02-25 EP disclosed
US-20260002121-A1 IMPROVED METHODS OF PREPARING DIFFERENT MESODERM CELL TYPES CHILDRENS HOSPITAL MED CT (US) 2026-01-01 US disclosed
US-20250388910-A1 METHODS FOR ENHANCING MICROBIAL PRODUCTION OF SPECIFIC LENGTH FATTY ALCOHOLS IN THE PRESENCE OF METHANOL AGAIN BIO APS (DK) 2025-12-25 US disclosed
US-20250340835-A1 VASCULARIZED BRAIN ORGANOIDS AND METHODS OF MAKING AND USE CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2025-11-06 US disclosed
WO-2009011870-A1 REDUCTION OF BETA-AMYLOID LEVELS BY TREATMENT WITH THE SMALL MOLECULE DIFFERENTIATION-INDUCING FACTOR THE GENERAL HOSPITAL CORPORATION (US) 2009-01-22 WO disclosed
JP-2005289891-A PDE1 INHIBITOR KUBOHARA ZEN 2005-10-20 JP disclosed
US-6888033-B1 Anti-viral compounds CYTOCLONAL PHARMACEUTICS, INC. (US) 2005-05-03 US disclosed
EP-0363392-A1 SUBSTITUTED PHENONE IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) 1990-04-18 EP disclosed
WO-1988009321-A1 SUBSTITUTED PHENONE 3I RESEARCH EXPLOITATION LIMITED (GB) 1988-12-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388910-A1 METHODS FOR ENHANCING MICROBIAL PRODUCTION OF SPECIFIC LENGTH FATTY ALCOHOLS IN THE PRESENCE OF METHANOL ADH5, ADH1C, ADH1A MEN1 4581/4885KMT2A 2260/4885PAK1 3759/4885
US-20260002121-A1 IMPROVED METHODS OF PREPARING DIFFERENT MESODERM CELL TYPES BMP4, RARB, WNT3A MEN1 3134/4885KMT2A 2242/4885PAK1 965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.