SCHEMBL3515342

SCHEMBL3515342

NC1(COc2ccccc2)COC1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.41
TDP1 Q9NUW8 1/20 0.40
KCNA3 P22001 1/20 0.40
ALDH1A1 P00352 1/20 0.36
RECQL P46063 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36
SCN4A P35499 2/20 0.36
LTA4H P09960 1/20 0.36
PLA2G2A P14555 1/20 0.36
AOC3 Q16853 1/20 0.36
HTR1A P08908 1/20 0.35
ADRA1A P35348 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1824875 0.82 MAOA (0.48) TAAR1TDP1KCNA3ALDH1A1RECQL
SCHEMBL12170820 0.81 WDR5 (0.41) ALDH1A1
SCHEMBL2850237 0.80 KCNA3 (0.43) TAAR1TDP1KCNA3ALDH1A1RECQL
SCHEMBL12170819 0.79 ALDH1A1 (0.44) ALDH1A1
SCHEMBL4205437 0.78 TAAR1 (0.42) TAAR1TDP1KCNA3ALDH1A1RECQL
SCHEMBL3048952 0.77 ACACB (0.44) TAAR1TDP1KCNA3ALDH1A1RECQL
SCHEMBL9080688 0.74 TDP1 (0.38) TAAR1TDP1KCNA3ALDH1A1RECQL
SCHEMBL36030 0.74 MEN1 (0.41) TDP1KCNA3CHRNB2CHRNB4CHRNA3
SCHEMBL1714455 0.74 ALDH1A1 (0.42) TDP1KCNA3ALDH1A1RECQL
SCHEMBL3512638 0.74 PARP10 (0.42) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4429872-A1 VAT POLYMERIZATION PROCESS Polyfos 3D Ltd (IL) 2024-09-18 EP claimed
WO-2023084517-A1 VAT POLYMERIZATION PROCESS POLYFOS 3D LTD (IL) 2023-05-19 WO claimed
US-20100311729-A1 Substituted imidazopyridazines and pyrrolopyrimidines as lipid kinase inhibitors CAPRARO HANS-GEORG 2010-12-09 US claimed
EP-2155202-A2 3,6-DISUBSTITUTED-IMIDAZO[1,2-B]PYRIDAZINES AND 3,5-DISUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINES AS PHOSPHATIDYLINOSITOL-3-KINASE INHIBITORS Novartis Ag (CH) 2010-02-24 EP claimed
WO-2008138889-A2 3, 6-DISUBSTITUTED-IMIDAZO [1, 2-B] PYRIDAZINES AND 3, 5-DISUBSTITUTED PYRAZOLO[1, 5-A] PYRIMIDINES AS PHOSPHATIDYLINOSITOL-3-KINASE INHIBITORS NOVARTIS AG (CH) 2008-11-20 WO claimed
US-20250010542-A1 VAT POLYMERIZATION PROCESS POLYFOS 3D LTD (IL) 2025-01-09 US disclosed
EP-4429872-A1 VAT POLYMERIZATION PROCESS Polyfos 3D Ltd (IL) 2024-09-18 EP disclosed
WO-2023084517-A1 VAT POLYMERIZATION PROCESS POLYFOS 3D LTD (IL) 2023-05-19 WO disclosed
US-11498268-B2 Method of making 3D printed objects by dispensing sequential layers of material PHOTOCENTRIC LIMITED (GB) 2022-11-15 US disclosed
US-11491711-B2 Method of making 3D printed objects using two distinct light sources PHOTOCENTRIC LIMITED (GB) 2022-11-08 US disclosed
US-20200282637-A1 METHOD OF MAKING 3D PRINTED OBJECTS BY DISPENSING SEQUENTIAL LAYERS OF MATERIAL PHOTOCENTRIC LIMITED (GB) 2020-09-10 US disclosed
US-20200282638-A1 METHOD OF MAKING 3D PRINTED OBJECTS USING TWO DISTINCT LIGHT SOURCES PHOTOCENTRIC LIMITED (GB) 2020-09-10 US disclosed
US-20100311729-A1 Substituted imidazopyridazines and pyrrolopyrimidines as lipid kinase inhibitors CAPRARO HANS-GEORG 2010-12-09 US disclosed
EP-2155202-A2 3,6-DISUBSTITUTED-IMIDAZO[1,2-B]PYRIDAZINES AND 3,5-DISUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINES AS PHOSPHATIDYLINOSITOL-3-KINASE INHIBITORS Novartis Ag (CH) 2010-02-24 EP disclosed
WO-2008138889-A2 3, 6-DISUBSTITUTED-IMIDAZO [1, 2-B] PYRIDAZINES AND 3, 5-DISUBSTITUTED PYRAZOLO[1, 5-A] PYRIMIDINES AS PHOSPHATIDYLINOSITOL-3-KINASE INHIBITORS NOVARTIS AG (CH) 2008-11-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311729-A1 Substituted imidazopyridazines and pyrrolopyrimidines as lipid kinase inhibitors PI4KA, PIP5K1B, PIP4K2A TAAR1 4501/4885TDP1 2767/4885KCNA3 4127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.