Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iopamidol SCHEMBL471484 | 0.86 | LMNA (1.00) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| Iopamidol SCHEMBL7101453 | 0.86 | LMNA (1.00) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| Iopamidol SCHEMBL27781 | 0.86 | LMNA (1.00) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL9352723 | 0.83 | LMNA (0.62) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL7591801 | 0.82 | LMNA (0.62) | LMNASMN1; SMN2 | |
| Iopamidol SCHEMBL3424448 | 0.82 | LMNA (0.92) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL22006124 | 0.82 | LMNA (0.92) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| Iopamidol SCHEMBL2140144 | 0.82 | LMNA (0.92) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL31409203 | 0.81 | LMNA (0.90) | LMNACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL7709204 | 0.81 | LMNA (0.90) | LMNACYP2C19HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100284919-A1 | Injectable Radio-Opaque Compositions for Tissue Augmentation | KUROS BIOSURGERY AG (CH) | 2010-11-11 | — | — | US | disclosed |