Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.33 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.33 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.33 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL475736 | 0.98 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3269103 | 0.98 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| Bromide SCHEMBL4592298 | 0.93 | TSHR (0.64) | TSHRTHRBPOLBAPEX1HTT | |
| Hydrochloric Acid SCHEMBL2798756 | 0.93 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| Hydrochloric Acid SCHEMBL27656623 | 0.91 | TSHR (0.66) | TSHRTHRBPOLBAPEX1HTT | |
| Hydrochloric Acid SCHEMBL27656702 | 0.91 | TSHR (0.66) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL6863232 | 0.91 | TSHR (0.66) | TSHRTHRBPOLBAPEX1HTT | |
| Bromide SCHEMBL4541172 | 0.89 | THRB (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1044534 | 0.87 | THRB (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| Hydrochloric Acid SCHEMBL475918 | 0.87 | THRB (0.55) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225192-B1 | PHOTOSENSITIVE RESIN COMPOSITION AND METHOD OF MANUFACTURING COLOR FILTER USING THE SAME | KABUSHIKI KAISHA TOSHIBA (JP) | 1991-10-09 | — | — | EP | claimed |
| US-4820619-A | COPOLYMER OF GLYCIDYL (METH-) ACRYLATE OR VINYL ETHER) WITH (METH-) ACRYLIC AMIDE OR ESTER HAVING QUATERNARY AMMONIUM SALT | KABUSHIKI KAISHA TOSHIBA (JP) | 1989-04-11 | — | — | US | claimed |
| EP-0225192-A2 | Photosensitive resin composition and method of manufacturing color filter using the same | KABUSHIKI KAISHA TOSHIBA (JP) | 1987-06-10 | — | — | EP | claimed |
| EP-2367852-B1 | COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS | SEDERMA SA (FR) | 2023-08-30 | — | — | EP | disclosed |
| EP-3744729-B1 | PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMOPHARMACEUTICAL USES | SEDERMA SA (FR) | 2023-03-01 | — | — | EP | disclosed |
| US-11166885-B2 | Personal care gel and method | COLGATE-PALMOLIVE COMPANY (US) | 2021-11-09 | — | — | US | disclosed |
| EP-3506873-B1 | PERSONAL CARE GEL AND METHOD | COLGATE PALMOLIVE CO (US) | 2021-11-03 | — | — | EP | disclosed |
| EP-3744729-A1 | COMPOUNDS, IN PARTICULAR PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMOPHARMACEUTICAL USES | SEDERMA (FR) | 2020-12-02 | — | — | EP | disclosed |
| US-10842728-B2 | Light-absorbing compositions and methods of use | ALLELE BIOTECHNOLOGY & PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| EP-3672520-A1 | LIGHT-ABSORBING COMPOSITIONS AND METHODS OF USE | Allele Biotechnology And Pharmaceuticals, Inc. (US) | 2020-07-01 | — | — | EP | disclosed |
| US-20190209442-A1 | Personal Care Gel and Method | COLGATE-PALMOLIVE COMPANY (US) | 2019-07-11 | — | — | US | disclosed |
| EP-0600008-A1 | HAIR SPRAY COMPOSITIONS WITH IONIC STYLING POLYMER | THE PROCTER & GAMBLE COMPANY (US) | 1994-06-08 | — | — | EP | disclosed |
| US-5277899-A | Quaternary ammonium surfactant | THE PROCTER & GAMBLE COMPANY (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0576578-A1 | COSMETIC COMPOSITIONS CONTAINING HYDROPHOBICALLY MODIFIED NONIONIC POLYMER AND UNSATURATED QUATERNARY AMMONIUM SURFACTANT. | PROCTER & GAMBLE (US) | 1994-01-05 | — | — | EP | disclosed |
| WO-1993007848-A2 | HAIR SETTING COMPOSITION WITH COMBINATION OF CATIONIC CONDITIONERS | THE PROCTER & GAMBLE COMPANY (US) | 1993-04-29 | — | — | WO | disclosed |
| WO-1993003704-A1 | HAIR SPRAY COMPOSITIONS WITH IONIC STYLING POLYMER | THE PROCTER & GAMBLE COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |
| WO-1993003703-A2 | HAIR SPRAY COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |
| WO-1992016187-A1 | COSMETIC COMPOSITIONS CONTAINING HYDROPHOBICALLY MODIFIED NONIONIC POLYMER AND UNSATURATED QUATERNARY AMMONIUM SURFACTANT | THE PROCTER & GAMBLE COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |
| EP-0225192-B1 | PHOTOSENSITIVE RESIN COMPOSITION AND METHOD OF MANUFACTURING COLOR FILTER USING THE SAME | KABUSHIKI KAISHA TOSHIBA (JP) | 1991-10-09 | — | — | EP | disclosed |
| EP-0225192-A2 | Photosensitive resin composition and method of manufacturing color filter using the same | KABUSHIKI KAISHA TOSHIBA (JP) | 1987-06-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11166885-B2 | Personal care gel and method | CUTA, GLMN, ISG15 | CHRM1 1708/4885CHRM3 1352/4885CHRM2 1890/4885 |
| US-10842728-B2 | Light-absorbing compositions and methods of use | CYBA, BROX, S100A6 | CHRM1 2579/4885CHRM3 2693/4885CHRM2 2516/4885 |
| US-20190209442-A1 | Personal Care Gel and Method | CUTA, GLMN, ISG15 | CHRM1 1708/4885CHRM3 1352/4885CHRM2 1890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.