Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 8/20 | 0.46 |
| ▸ | CCR9 | P51686 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3528825 | 0.94 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ASLC16A3CCR9 | |
| SCHEMBL3523698 | 0.89 | ERBB2 (0.50) | ALDH1A1MEN1KMT2ACCR9CCR2 | |
| SCHEMBL3525803 | 0.89 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ACCR9CCR2 | |
| SCHEMBL3523907 | 0.88 | CYP2C9 (0.47) | CCR9 | |
| SCHEMBL3521448 | 0.87 | ACLY (0.50) | ALDH1A1CCR9 | |
| SCHEMBL3527490 | 0.87 | LMNA (0.53) | ALDH1A1MEN1KMT2ASLC16A3CCR9 | |
| SCHEMBL3528317 | 0.86 | SLC16A3 (0.49) | ALDH1A1MEN1KMT2ASLC16A3CCR9 | |
| SCHEMBL3523501 | 0.86 | CCR2 (0.47) | ALDH1A1MEN1KMT2ACCR9CCR2 | |
| SCHEMBL3527669 | 0.86 | LMNA (0.48) | ALDH1A1KMT2ACCR9CCR2 | |
| SCHEMBL3522957 | 0.85 | FLT1 (0.43) | ALDH1A1KMT2ACCR9CCR2FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436040-B2 | Method of treating conditions involving PPAR-receptors with indole compounds | LABORATOIRES FOURNIER S.A. (FR) | 2013-05-07 | — | — | US | disclosed |
| US-20100286137-A1 | Method of Treating Conditions Involving PPAR-Receptors with Indole Compounds | LABORATORIES FOURNIER S.A. (FR) | 2010-11-11 | — | — | US | disclosed |
| US-7795297-B2 | Indole compounds, method of preparing them and uses thereof | LABORATORIES FOURNIER S.A. (FR) | 2010-09-14 | — | — | US | disclosed |
| US-20080153816-A1 | Indole Compounds, Method of Preparing Them and Uses Thereof | LABORATOIRES FOURNIER S.A. (FR) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153816-A1 | Indole Compounds, Method of Preparing Them and Uses Thereof | LIPG, GPR119, IAPP | ALDH1A1 1607/4885MEN1 2711/4885KMT2A 2305/4885 |
| US-20100286137-A1 | Method of Treating Conditions Involving PPAR-Receptors with Indole Compounds | GPR119, PPARA, PPARG | ALDH1A1 1453/4885MEN1 4787/4885KMT2A 2990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.