Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 9/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.34 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27139253 | 1.00 | GPR84 (0.43) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL21645392 | 1.00 | GPR84 (0.43) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL499152 | 0.98 | GPR84 (0.39) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL6541852 | 0.91 | CAMK2A (0.39) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL29991123 | 0.91 | ALDH1A1 (0.41) | ALDH1A1KDM5AKDM4AKDM4CKDM7A | |
| SCHEMBL24703880 | 0.89 | ALDH1A1 (0.42) | ALDH1A1KDM5AKDM4AKDM4CKDM7A | |
| SCHEMBL22205611 | 0.84 | LMNA (0.44) | ALDH1A1KDM5AKDM4AKDM4CKDM7A | |
| SCHEMBL3963400 | 0.83 | ALDH1A1 (0.50) | GPR84FFAR1FFAR4ALDH1A1KDM5A | |
| SCHEMBL8142273 | 0.83 | ALDH1A1 (0.50) | GPR84FFAR1FFAR4ALDH1A1KDM5A | |
| SCHEMBL2304549 | 0.83 | ALDH1A1 (0.50) | GPR84FFAR1FFAR4ALDH1A1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691900-B2 | Tocopherol derivatives with a long hydroxylated chain, which can be used as neurotrophics | AXOGLIA THERAPEUTICS S.A. (LU) | 2010-04-06 | — | — | US | disclosed |
| US-20070105946-A1 | Tocopherol derivatives with a long hydroxylated chain, which can be used as neurotrophics | UNIVERSITE LOUIS PASTEUR (FR) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105946-A1 | Tocopherol derivatives with a long hydroxylated chain, which can be used as neurotrophics | BDNF, GMFG, NGF | GPR84 337/4885FFAR1 220/4885FFAR4 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.