Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31290723 | 1.00 | PIM1 (0.74) | PIM1ALDH1A1KDM4EKMT2ACA12 | |
| SCHEMBL2761544 | 0.85 | PIM1 (1.00) | PIM1ALDH1A1KDM4EKMT2ACA12 | |
| SCHEMBL23640512 | 0.82 | PIM1 (0.64) | PIM1ALDH1A1KDM4EKMT2ACA12 | |
| SCHEMBL958685 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KDM4EKMT2ACA12CA9 | |
| SCHEMBL29419327 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KDM4EKMT2ACA12CA9 | |
| Water SCHEMBL11848480 | 0.79 | ALDH1A1 (0.96) | ALDH1A1KDM4EKMT2ACA12CA9 | |
| SCHEMBL8119361 | 0.78 | ALDH1A1 (0.68) | PIM1ALDH1A1KDM4EKMT2ACA12 | |
| SCHEMBL2761833 | 0.78 | ALDH1A1 (0.68) | PIM1ALDH1A1KDM4EKMT2ACA12 | |
| SCHEMBL14492920 | 0.78 | ALDH1A1 (0.68) | PIM1ALDH1A1KDM4EKMT2ACA12 | |
| SCHEMBL5346628 | 0.78 | ALDH1A1 (0.68) | PIM1ALDH1A1KDM4EKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178385-B | Coumarin hemicyanine dye with structural rigidity, and preparation method and application thereof | 山西大学 | 2025-01-28 | — | — | CN | claimed |
| CN-116178385-A | Coumarin hemicyanine dye with structural rigidity, and preparation method and application thereof | 山西大学 | 2023-05-30 | — | — | CN | claimed |
| CN-106008475-A | Coumarin NEDD8 activating enzyme inhibitor | 南京工业大学 | 2016-10-12 | — | — | CN | claimed |
| EP-4735452-A2 | HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF KRAS PROTEIN | Merck Patent GmbH (DE) | 2026-05-06 | — | — | EP | disclosed |
| EP-4735438-A2 | HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF KRAS | Merck Patent GmbH (DE) | 2026-05-06 | — | — | EP | disclosed |
| US-20250326732-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2025-10-23 | — | — | US | disclosed |
| CN-116178385-B | Coumarin hemicyanine dye with structural rigidity, and preparation method and application thereof | 山西大学 | 2025-01-28 | — | — | CN | disclosed |
| WO-2025006753-A2 | HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF KRAS PROTEIN | MERCK PATENT GMBH (DE) | 2025-01-02 | — | — | WO | disclosed |
| WO-2025006783-A2 | HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF KRAS | MERCK PATENT GMBH (DE) | 2025-01-02 | — | — | WO | disclosed |
| CN-115160300-B | Coumarin compound, preparation method thereof and application of coumarin compound in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2024-05-31 | — | — | CN | disclosed |
| CN-116178385-A | Coumarin hemicyanine dye with structural rigidity, and preparation method and application thereof | 山西大学 | 2023-05-30 | — | — | CN | disclosed |
| US-20070149579-A1 | Novel pharmaceutical compounds | MERCK CANADA INC. (CA) | 2007-06-28 | — | — | US | disclosed |
| EP-1531812-B1 | FUSED HETEROARYL DERIVATIVES FOR USE AS P38 KINASE INHIBITORS IN THE TREATMENT OF I.A. RHEUMATOID ARTHRITIS | SMITHKLINE BEECHAM CORP (US) | 2007-06-27 | — | — | EP | disclosed |
| US-20070054942-A1 | Fused heteroaryl derivatives and their use as p38 kinase inhibitors | GLAXOSMITHKLINE LLC | 2007-03-08 | — | — | US | disclosed |
| US-20060122221-A1 | Fused heteroaryl derivatives for use as p38 kinase inhibitors in the treatment of i.a. rheumatoid arthristis | SMITHKLINE BEECHAM CORPORATION | 2006-06-08 | — | — | US | disclosed |
| EP-1531812-A1 | FUSED HETEROARYL DERIVATIVES FOR USE AS P38 KINASE INHIBITORS IN THE TREATMENT OF I.A. RHEUMATOID ARTHRISTIS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004010995-A1 | FUSED HETEROARYL DERIVATIVES FOR USE AS P38 KINASE INHIBITORS IN THE TREATMENT OF I.A. RHEUMATOID ARTHRISTIS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-3974289-A | Coumarin derivatives for the treatment of allergies | BEECHAM GROUP LIMITED (EN) | 1976-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326732-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | POLRMT, TFAM, POLM | PIM1 2621/4885ALDH1A1 3178/4885KDM4E 2158/4885 |
| US-20060122221-A1 | Fused heteroaryl derivatives for use as p38 kinase inhibitors in the treatment of i.a. rheumatoid arthristis | MAPK7, CNKSR1, MAPK1 | PIM1 2055/4885ALDH1A1 1269/4885KDM4E 4559/4885 |
| US-20070149579-A1 | Novel pharmaceutical compounds | LTA4H, LTB4R2, LTC4S | PIM1 2670/4885ALDH1A1 431/4885KDM4E 3391/4885 |
| US-20070054942-A1 | Fused heteroaryl derivatives and their use as p38 kinase inhibitors | MAPK1, MAPK7, MAPKAPK2 | PIM1 1126/4885ALDH1A1 2057/4885KDM4E 4697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.