Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL2192190 | 0.84 | — | — | |
| SCHEMBL25008 | 0.84 | — | — | |
| Methyl Alcohol SCHEMBL7165044 | 0.78 | — | — | |
| Methyl Alcohol SCHEMBL16240074 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TDP1LOXLOXL3LOXL2 | |
| SCHEMBL11319645 | 0.78 | — | — | |
| Formic Acid SCHEMBL1832589 | 0.77 | — | — | |
| Sulfuric Acid SCHEMBL11400474 | 0.77 | NLRP3 (0.42) | ALDH1A1TDP1LOXLOXL3LOXL2 | |
| Formic Acid SCHEMBL16537541 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TDP1LOXLOXL3LOXL2 | |
| Formic Acid SCHEMBL16536323 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TDP1LOXLOXL3LOXL2 | |
| Methylene Chloride SCHEMBL4677589 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103713064-B | Method for determining related substances of bismuthyl ecabet by using high performance liquid chromatography | ZHUHAI EBANG PHARMACEUTICAL CO LTD | 2015-03-11 | — | — | CN | claimed |
| CN-101406463-A | Method for preparing metronidazole, clotrimazole and chlorhexidime vaginal acetate effervescent tablet and quality control method | SHIFENG WANG (CN) | 2009-04-15 | — | — | CN | claimed |
| CN-101283989-A | Metronidazole vaginal tablet process and quality control method | HE WENJIAN (CN) | 2008-10-15 | — | — | CN | claimed |
| CN-118236338-A | Preparation method of voronoi fumarate preparation | 寿光富康制药有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-117741008-A | Method for detecting content of amoenavir in amoenavir tablet by adopting high performance liquid chromatography | 吉斯凯(苏州)制药有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-114848834-B | Double-drug co-delivery composite multilayer nano-carrier and preparation method and application thereof | 浙江大学医学院附属第一医院 | 2024-01-26 | — | — | CN | disclosed |
| CN-114344473-B | Antitumor drug delivery system and preparation method and application thereof | 上海交通大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-116973473-A | Related substance detection method of felodipine | 湖南九典宏阳制药有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116699013-A | Method for separating and detecting related impurities in oseltamium phosphate Wei Kou disintegrating tablet | 北京星昊医药股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-3927719-B9 | DIETHYLAMINE SALT OF 3ALPHA-TETRAHYDROPYRANYLOXY-6ALPHA-ETHYL-7ALPHA-HYDROXY-5BETA-CHOLANIC ACID | MOEHS IBERICA SL (ES) | 2023-08-23 | — | — | EP | disclosed |
| CN-115894515-A | Method for integrated extraction, enrichment, separation and purification of effective components of ginkgo leaves in full industrial chain | 李玉山 | 2023-04-04 | — | — | CN | disclosed |
| EP-1594862-B1 | METHODS OF MAKING 6-[ (4,5-DIHYDRO-1H-IMIDAZOL-2-YL)AMINO-] -7-METHYL-1H-BENZIMIDAZOLE-4-CARBONITRILE AND ITS PREFERRED SALT FORM | UNIV NEBRASKA (US) | 2008-11-19 | — | — | EP | disclosed |
| CN-101283989-A | Metronidazole vaginal tablet process and quality control method | HE WENJIAN (CN) | 2008-10-15 | — | — | CN | disclosed |
| EP-1953146-A1 | Methods of making 6-[(4,5-Dihydro-1H-imidazol-2-yl) amino-]-7-methyl-1H-benzimidazole-4-carbonitrile and its preferred salt form | The Board of Regents of the University of Nebraska (US) | 2008-08-06 | — | — | EP | disclosed |
| US-7304084-B2 | 6-[(4,5-Dihydro-1H-imidazol-2-yl)amino]-7-methyl-1H-benzimidazole-4-carbonitrile and its preferred salt | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2007-12-04 | — | — | US | disclosed |
| US-20060122248-A1 | Methods of making 6-[(4,5-dihydro-1H-imidazol-2-yl)amino-]-7-methyl-1H-benzimidazole-4-carbonitrile and its preferred salt form | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2006-06-08 | — | — | US | disclosed |
| EP-1594862-A1 | METHODS OF MAKING 6- (4,5-DIHYDRO-1H-IMIDAZOL-2-YL)AMINO-&rs qb;-7-METHYL-1H-BENZIMIDAZOLE-4-CARBONITRILE AND ITS PREFERRED SALT FORM | The Board of Regents of the University of Nebraska (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004074279-A1 | METHODS OF MAKING 6-[(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)AMINO-]-7-METHYL-1H-BENZIMIDAZOLE-4-CARBONITRILE AND ITS PREFERRED SALT FORM | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2004-09-02 | — | — | WO | disclosed |
| US-20040167194-A1 | Methods of making 6-[(4,5-Dihydro-1H-imidazol-2-yl)amino-]-7-methyl-1H-benzimidazole-4-carbonitrile and its preferred salt form | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2004-08-26 | — | — | US | disclosed |
| EP-0172873-B1 | AN ERECTION AND FERTILITY PROMOTING AGENT, A METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF IN THE PRODUCTION OF ERECTION AND FERTILITY PROMOTING COMPOSITIONS | FERRING B.V. (NL) | 1989-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167194-A1 | Methods of making 6-[(4,5-Dihydro-1H-imidazol-2-yl)amino-]-7-methyl-1H-benzimidazole-4-carbonitrile and its preferred salt form | AGTR2, ALDH1A2, REN | ALDH1A1 196/4885TDP1 4251/4885LOX 3519/4885 |
| US-20060122248-A1 | Methods of making 6-[(4,5-dihydro-1H-imidazol-2-yl)amino-]-7-methyl-1H-benzimidazole-4-carbonitrile and its preferred salt form | AGTR2, ALDH1A2, REN | ALDH1A1 119/4885TDP1 4339/4885LOX 3448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.