Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 4/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354475 | 0.89 | HTT (0.40) | TSHRHTTMEN1KMT2ARAD52 | |
| SCHEMBL352456 | 0.86 | HCRTR1 (0.39) | HCRTR1HCRTR2TSHRMEN1KMT2A | |
| SCHEMBL353355 | 0.85 | KMT2A (0.36) | HCRTR1HCRTR2HTTMEN1KMT2A | |
| SCHEMBL353612 | 0.83 | MEN1 (0.35) | HCRTR1HCRTR2HTTMEN1KMT2A | |
| SCHEMBL10167495 | 0.82 | MEN1 (0.41) | HCRTR1HCRTR2TSHRHTTMEN1 | |
| SCHEMBL10167509 | 0.79 | RAD52 (0.51) | TSHRHTTMEN1KMT2ARAD52 | |
| SCHEMBL352691 | 0.73 | KMT2A (0.39) | HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL357050 | 0.72 | KDM4E (0.34) | HCRTR1HCRTR2HTTMEN1KMT2A | |
| SCHEMBL10167556 | 0.68 | KMT2A (0.35) | HCRTR1HCRTR2MEN1KMT2ARAD52 | |
| SCHEMBL353613 | 0.68 | MAPT (0.44) | HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |