Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352691 | 0.90 | KMT2A (0.39) | KMT2ASMN1; SMN2LMNAMEN1ALDH1A1 | |
| SCHEMBL353442 | 0.89 | LMNA (0.36) | KMT2ASMN1; SMN2LMNAMEN1ALDH1A1 | |
| SCHEMBL358113 | 0.85 | KMT2A (0.40) | KMT2ASMN1; SMN2LMNAMEN1ALDH1A1 | |
| SCHEMBL353134 | 0.85 | HCRTR1 (0.39) | KMT2AMEN1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL10167556 | 0.84 | KMT2A (0.35) | KMT2ASMN1; SMN2LMNAMEN1ALDH1A1 | |
| SCHEMBL10167584 | 0.82 | L3MBTL1 (0.42) | KMT2ASMN1; SMN2LMNAMEN1ALDH1A1 | |
| SCHEMBL352456 | 0.81 | HCRTR1 (0.39) | KMT2AMEN1ALDH1A1MAPTHCRTR1 | |
| SCHEMBL354766 | 0.76 | HCRTR1 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL354475 | 0.74 | HTT (0.40) | KMT2ASMN1; SMN2LMNAMEN1ALDH1A1 | |
| SCHEMBL351633 | 0.71 | KMT2A (0.40) | KMT2ASMN1; SMN2LMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |