Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3526711 | 0.81 | HPN (0.51) | MAPTKMT2AMEN1LMNARAB9A | |
| SCHEMBL6480240 | 0.69 | LMNA (0.43) | MAPTKMT2AMEN1LMNAHTT | |
| SCHEMBL16702434 | 0.69 | SIRT6 (0.45) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL10643664 | 0.67 | SCN2A (0.54) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL5314594 | 0.67 | SIRT6 (0.46) | MAPTKMT2AMEN1LMNASIRT6 | |
| SCHEMBL9187712 | 0.66 | GSK3A (0.56) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL22567 | 0.66 | ALDH1A1 (0.72) | KMT2AMEN1LMNAALDH1A1MAPK1 | |
| SCHEMBL27909482 | 0.66 | ALDH1A1 (0.72) | KMT2AMEN1LMNAALDH1A1MAPK1 | |
| SCHEMBL31011685 | 0.66 | MAPT (0.56) | MAPTKMT2AMEN1LMNARAB9A | |
| SCHEMBL517098 | 0.66 | GSK3A (0.52) | MAPTKMT2AMEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745620-B2 | Disubstituted cucurbiturils and preparing method thereof | POSTECH FOUNDATION (KR) | 2010-06-29 | — | — | US | disclosed |
| US-20080139821-A1 | Disubstituted Cucurbiturils and Preparing Method Thereof | POSTECH FOUNDATION (KR) | 2008-06-12 | — | — | US | disclosed |
| WO-2005087777-A1 | DISTRIBUTED CUCURBITURILS AND PREPARING METHOD THEREOF | POSTECH FOUNDATION (KR) | 2005-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139821-A1 | Disubstituted Cucurbiturils and Preparing Method Thereof | AGL, UCHL1, SCLY | MAPT 4548/4885KMT2A 1444/4885MEN1 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.