Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12376581 | 0.83 | MITF (0.56) | MITFPLK1HDAC6KLK7ALDH1A1 | |
| SCHEMBL13078563 | 0.79 | ALDH1A1 (0.44) | MITFSMN1; SMN2HDAC4HDAC6ALDH1A1 | |
| SCHEMBL1434936 | 0.76 | TDP1 (0.45) | SMN1; SMN2ALDH1A1POLBLMNAHPGD | |
| SCHEMBL28182643 | 0.76 | MAOA (0.39) | HDAC4HDAC6ALDH1A1LMNA | |
| SCHEMBL3064032 | 0.75 | GRM8 (0.33) | MITFSMN1; SMN2HDAC4HDAC6ALDH1A1 | |
| SCHEMBL15652003 | 0.75 | LMNA (0.42) | ALDH1A1KDM4EPOLBLMNAHPGD | |
| SCHEMBL13044116 | 0.74 | SMN1; SMN2 (0.35) | MITFSMN1; SMN2HDAC4HDAC6KDM4E | |
| SCHEMBL20188227 | 0.73 | S1PR4 (0.54) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2303628 | 0.72 | KLK7 (0.66) | SMN1; SMN2KLK7ALDH1A1KDM4ENPC1 | |
| SCHEMBL4146465 | 0.72 | TDP1 (0.45) | PLK1KLK7ALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148380-B2 | Antibacterial amide and sulfonamide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | NAAA, AADAC, RPSA | MITF 2435/4885PLK1 4007/4885SMN1; SMN2 2356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.