Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27685285 | 0.87 | CYP4A11 (0.41) | LOXL2SENP1MEN1KMT2AMAPK1 | |
| SCHEMBL5889497 | 0.85 | SENP1 (0.47) | SENP1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL2937165 | 0.84 | HPGD (0.43) | LOXL2SENP1MEN1KMT2AMAPK1 | |
| SCHEMBL23235066 | 0.80 | RAB9A (0.49) | CES2CES1SENP1MEN1KMT2A | |
| SCHEMBL15712039 | 0.78 | TDP1 (0.55) | CES2CES1KMT2AMAPTTDP1 | |
| SCHEMBL10126445 | 0.78 | SENP1 (0.59) | SENP1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL8712521 | 0.78 | CA1 (0.55) | LOXL2MEN1KMT2AMAPK1POLB | |
| SCHEMBL19543203 | 0.78 | ALDH1A1 (0.47) | LOXL2MEN1KMT2APOLBMAPT | |
| SCHEMBL8159484 | 0.77 | CES2 (0.53) | CES2CES1LOXL2MEN1KMT2A | |
| SCHEMBL11355161 | 0.77 | CES2 (0.42) | CES2CES1SENP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339993-A1 | Aptamer Conjugates with N-Heterocyclic Carbene Metal Complexes for Targeted Drug Delivery | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC. | 2020-10-29 | — | — | US | disclosed |
| US-10731164-B2 | Aptamer conjugates with N-heterocyclic carbene metal complexes for targeted drug delivery | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2020-08-04 | — | — | US | disclosed |
| US-20170107516-A1 | Aptamer Conjugates With N-Heterocyclic Carbene Metal Complexes for Targeted Drug Delivery | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2017-04-20 | — | — | US | disclosed |
| US-20150139901-A1 | Radioactive Rhodium Complexes, Preparation Methods and Uses Thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE (INSERM) (FR) | 2015-05-21 | — | — | US | disclosed |
| US-20150139901-A1 | Radioactive Rhodium Complexes, Preparation Methods and Uses Thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE (INSERM) (FR) | 2015-05-21 | — | — | US | disclosed |
| US-20150139901-A1 | Radioactive Rhodium Complexes, Preparation Methods and Uses Thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE (INSERM) (FR) | 2015-05-21 | — | — | US | disclosed |
| EP-2850089-A1 | RADIOACTIVE RHODIUM COMPLEXES, PREPARATION METHODS AND USES THEREOF | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2015-03-25 | — | — | EP | disclosed |
| WO-2013171224-A1 | RADIOACTIVE RHODIUM COMPLEXES, PREPARATION METHODS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2013-11-21 | — | — | WO | disclosed |
| US-7723529-B2 | Process for preparing nitrooxy esters, nitrooxy thioesters nitrooxy carbonates and nitrooxy thiocarbinates, intermediates useful in said process and preparation thereof | NICOX S.A. (FR) | 2010-05-25 | — | — | US | disclosed |
| US-20070238882-A1 | Process for Preparing Nitrooxy Esters, Nitrooxy Thioesters Nitrooxy Carbonates and Nitrooxy Thiocarbinates, Intermediates Useful in Said Process and Preparation Thereof | NICOX S.A. (FR) | 2007-10-11 | — | — | US | disclosed |
| EP-1778617-A1 | PROCESS FOR PREPARING NITROOXY ESTERS, NITROOXY THIOESTERS, NITROOXY CARBONATES AND NITROOXY THIOCARBONATES, INTERMEDIATES USEFUL IN SAID PROCESS AND PREPARATION THEREOF | NicOx S.A. (FR) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006079610-A1 | NITROOXY SARTAN DERIVATIVES AS ANGIOTENSIN II RECEPTOR BLOCKERS FOR THE TREATMENT OF CARDIOVASCULAR AND INFLAMMATORY DISEASES | NICOX S.A. (FR) | 2006-08-03 | — | — | WO | disclosed |
| WO-2006008196-A1 | PROCESS FOR PREPARING NITROOXY ESTERS, NITROOXY THIOESTERS, NITROOXY CARBONATES AND NITROOXY THIOCARBONATES, INTERMEDIATES USEFUL IN SAID PROCESS AND PREPARATION THEREOF | NICOX S.A. (FR) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150139901-A1 | Radioactive Rhodium Complexes, Preparation Methods and Uses Thereof | RAB35, MRPL21, MRPS35 | CES2 2125/4885CES1 3203/4885LOXL2 4682/4885 |
| US-20170107516-A1 | Aptamer Conjugates With N-Heterocyclic Carbene Metal Complexes for Targeted Drug Delivery | NTPCR, NDC1, PAICS | CES2 1213/4885CES1 2030/4885LOXL2 4703/4885 |
| US-20070238882-A1 | Process for Preparing Nitrooxy Esters, Nitrooxy Thioesters Nitrooxy Carbonates and Nitrooxy Thiocarbinates, Intermediates Useful in Said Process and Preparation Thereof | OTUB1, TET1, TET3 | CES2 125/4885CES1 405/4885LOXL2 2692/4885 |
| US-10731164-B2 | Aptamer conjugates with N-heterocyclic carbene metal complexes for targeted drug delivery | NTPCR, NDC1, PAICS | CES2 1213/4885CES1 2030/4885LOXL2 4703/4885 |
| US-20200339993-A1 | Aptamer Conjugates with N-Heterocyclic Carbene Metal Complexes for Targeted Drug Delivery | NTPCR, NDC1, PAICS | CES2 1213/4885CES1 2030/4885LOXL2 4703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.