Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 4/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353612 | 0.86 | MEN1 (0.35) | HCRTR1HCRTR2ALDH1A1MEN1MAPK1 | |
| SCHEMBL353134 | 0.86 | HCRTR1 (0.39) | HCRTR1HCRTR2ALDH1A1TSHRMEN1 | |
| SCHEMBL354766 | 0.85 | HCRTR1 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL353355 | 0.81 | KMT2A (0.36) | HCRTR1HCRTR2ALDH1A1MEN1NPC1 | |
| SCHEMBL10167489 | 0.80 | HCRTR1 (0.38) | HCRTR1HCRTR2HTR2CALDH1A1TSHR | |
| SCHEMBL10167434 | 0.79 | ALDH1A1 (0.37) | HTR2CALDH1A1TSHRMEN1NPC1 | |
| SCHEMBL354277 | 0.78 | HCRTR1 (0.35) | HCRTR1HCRTR2KDM4E | |
| SCHEMBL292530 | 0.77 | KCNA5 (0.40) | MEN1KMT2A | |
| SCHEMBL357050 | 0.76 | KDM4E (0.34) | HCRTR1HCRTR2ALDH1A1MEN1RAB9A | |
| SCHEMBL354475 | 0.73 | HTT (0.40) | ALDH1A1TSHRMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |