Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354766 | 0.87 | HCRTR1 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL355401 | 0.82 | HPGD (0.34) | KDM4EHSD17B10SMN1; SMN2HPGDMEN1 | |
| SCHEMBL354277 | 0.82 | HCRTR1 (0.35) | KDM4EHCRTR1HCRTR2GRM5 | |
| SCHEMBL355455 | 0.80 | ALDH1A1 (0.38) | KDM4EHSD17B10SMN1; SMN2HPGDMEN1 | |
| SCHEMBL352456 | 0.76 | HCRTR1 (0.39) | KDM4EHSD17B10MEN1KMT2AHCRTR1 | |
| SCHEMBL353442 | 0.75 | LMNA (0.36) | SMN1; SMN2MEN1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL353612 | 0.72 | MEN1 (0.35) | KDM4EHSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL353134 | 0.72 | HCRTR1 (0.39) | HPGDMEN1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL352076 | 0.71 | HTR2C (0.34) | KDM4ESMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL10167484 | 0.70 | HCRTR1 (0.35) | KDM4EHSD17B10SMN1; SMN2HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |