Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351264 | 0.89 | MAPT (0.43) | MAPTALDH1A1NPSR1GAAGPBAR1 | |
| SCHEMBL10167582 | 0.88 | MAPT (0.56) | MAPTDGAT2ALDH1A1NPSR1GAA | |
| SCHEMBL10167652 | 0.77 | MAPT (0.46) | MAPTALDH1A1GPBAR1POLBNPC1 | |
| SCHEMBL354475 | 0.75 | HTT (0.40) | ALDH1A1NPC1HTT | |
| SCHEMBL10167648 | 0.75 | MAPT (0.59) | MAPTDGAT2GPBAR1 | |
| SCHEMBL10167558 | 0.73 | MAPT (0.49) | MAPTALDH1A1GPBAR1 | |
| SCHEMBL352691 | 0.71 | KMT2A (0.39) | MAPTALDH1A1POLBHTT | |
| SCHEMBL351052 | 0.71 | MEN1 (0.42) | MAPTALDH1A1KDM4EHTT | |
| SCHEMBL353134 | 0.68 | HCRTR1 (0.39) | ALDH1A1HTT | |
| SCHEMBL352456 | 0.67 | HCRTR1 (0.39) | MAPTALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |