SCHEMBL354701

SCHEMBL354701

N#CCC1C2CC3CC(C2)CC1C3

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.39
CYP2C9 P11712 1/20 0.33
DPP4 P27487 1/20 0.33
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9208229 0.75 HSD11B1 (0.37) HSD11B1CYP2C9
SCHEMBL15373721 0.75
SCHEMBL13976239 0.75
SCHEMBL339411 0.74 HSD11B1 (0.44) HSD11B1CYP2C9
SCHEMBL11721401 0.72 HSD11B1 (0.34) HSD11B1
SCHEMBL17931731 0.67
SCHEMBL25020522 0.64
SCHEMBL24277964 0.64 MEN1 (0.36) DPP4
SCHEMBL11626389 0.64
SCHEMBL5347659 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9840568-B2 Polymer and method for producing same MITSUBISHI CHEMICAL CORPORATION (JP) 2017-12-12 US claimed
US-20240092956-A1 Polymer, Resist Composition, Method for Manufacturing Substrate Having Pattern Formed Therein, and (Meth)Acrylic Ester and Production Method Therefor MITSUBISHI CHEMICAL CORPORATION (JP) 2024-03-21 US disclosed
US-11845822-B2 Polymer, resist composition, method for manufacturing substrate having pattern formed therein, and (meth) acrylic ester and production method therefor MITSUBISHI CHEMICAL CORPORATION (JP) 2023-12-19 US disclosed
US-20220213243-A1 Polymer, Resist Composition, Method for Manufacturing Substrate Having Pattern Formed Therein, and (Meth)Acrylic Ester and Production Method Therefor MITSUBISHI CHEMICAL CORPORATION (JP) 2022-07-07 US disclosed
CN-113614073-A Polymer, resist composition, method for producing substrate having pattern formed thereon, and (meth) acrylate and method for producing same 三菱化学株式会社 2021-11-05 CN disclosed
WO-2020196667-A1 POLYMER, RESIST COMPOSITION, METHOD FOR MANUFACTURING SUBSTRATE HAVING PATTERN FORMED THEREIN, AND (METH)ACRYLIC ESTER AND PRODUCTION METHOD THEREFOR 三菱ケミカル株式会社 2020-10-01 WO disclosed
US-10025188-B2 Resist pattern-forming method JSR CORPORATION (JP) 2018-07-17 US disclosed
US-9840568-B2 Polymer and method for producing same MITSUBISHI CHEMICAL CORPORATION (JP) 2017-12-12 US disclosed
US-20170322492-A1 RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2017-11-09 US disclosed
US-20160320705-A1 RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2016-11-03 US disclosed
EP-2615497-A1 RESIST PATTERN FORMING METHOD JSR Corporation (JP) 2013-07-17 EP disclosed
US-20120015911-A1 METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES BELLUS HEALTH INC. (CA) 2012-01-19 US disclosed
US-8044100-B2 Methods and compositions for treating amyloid-related diseases BELLUS HEALTH INC. (CA) 2011-10-25 US disclosed
CN-101128421-A Methods and compositions for treating amyloid-related diseases NEUROCHEM INTERNAT LTD (CH) 2008-02-20 CN disclosed
EP-1836161-A2 METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES Neurochem (International) Limited (CH) 2007-09-26 EP disclosed
EP-1731504-A1 ADAMANTANE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2006-12-13 EP disclosed
US-20060223855-A1 reduces or inhibits amyloid fibril formation, organ specific dysfunction (e.g., neurodegeneration), or cellular toxicity NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2006-10-05 US disclosed
WO-2006085149-A2 METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2006-08-17 WO disclosed
US-4064258-A Thiazole cardiovascular agents SYNTEX (U.S.A.) INC. (US) 1977-12-20 US disclosed
US-3962328-A VIRICIDES KAO SOAP CO., LTD. (JA) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223855-A1 reduces or inhibits amyloid fibril formation, organ specific dysfunction (e.g., neurodegeneration), or cellular toxicity APP, IAPP, BACE1 HSD11B1 2010/4885CYP2C9 3354/4885DPP4 594/4885
US-20220213243-A1 Polymer, Resist Composition, Method for Manufacturing Substrate Having Pattern Formed Therein, and (Meth)Acrylic Ester and Production Method Therefor ASS1, SETDB1, MAT1A HSD11B1 169/4885CYP2C9 1880/4885DPP4 4721/4885
US-20240092956-A1 Polymer, Resist Composition, Method for Manufacturing Substrate Having Pattern Formed Therein, and (Meth)Acrylic Ester and Production Method Therefor ASS1, SETDB1, MAT1A HSD11B1 169/4885CYP2C9 1880/4885DPP4 4721/4885
US-11845822-B2 Polymer, resist composition, method for manufacturing substrate having pattern formed therein, and (meth) acrylic ester and production method therefor ASS1, SETDB1, MAT1A HSD11B1 169/4885CYP2C9 1880/4885DPP4 4721/4885
US-20120015911-A1 METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES APP, PSEN1, PSEN2 HSD11B1 705/4885CYP2C9 2005/4885DPP4 996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.