Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1967290 | 1.00 | TACR1 (0.59) | TACR1TSHRSLC6A2TAAR1MAOA | |
| SCHEMBL507258 | 1.00 | TACR1 (0.59) | TACR1TSHRSLC6A2TAAR1MAOA | |
| Trifluoroacetic Acid SCHEMBL23390351 | 0.85 | SLC1A1 (0.51) | TACR1SLC6A2TAAR1MAOASLC6A4 | |
| Trifluoroacetic Acid SCHEMBL23390354 | 0.85 | SLC1A1 (0.51) | TACR1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL7421010 | 0.84 | TACR1 (0.66) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL7332866 | 0.84 | TACR1 (0.66) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL9677926 | 0.84 | TACR1 (0.66) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL22013212 | 0.83 | TACR1 (0.63) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL7095981 | 0.83 | TACR1 (0.75) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL18394417 | 0.83 | TACR1 (0.63) | TACR1TSHRCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260085067-A1 | CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF | BOUNDLESS BIO INC (US) | 2026-03-26 | — | — | US | disclosed |
| EP-4587437-A1 | CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF | Boundless Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| US-12195446-B2 | Heteroaryl compounds and their use as therapeutic drugs | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2025-01-14 | — | — | US | disclosed |
| US-20240294565-A1 | UNNATURAL CONFIGURATION NUCLEOTIDE PRODRUG COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED | 2024-09-05 | — | — | US | disclosed |
| WO-2024059563-A1 | CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| US-20230295152-A1 | PYRIDOPYRIMIDINONE DERIVATIVES AS AHR ANTAGONISTS | SENDA BIOSCIENCES, INC. (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230295152-A1 | PYRIDOPYRIMIDINONE DERIVATIVES AS AHR ANTAGONISTS | SENDA BIOSCIENCES, INC. (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230295152-A1 | PYRIDOPYRIMIDINONE DERIVATIVES AS AHR ANTAGONISTS | SENDA BIOSCIENCES, INC. (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2023-01-05 | — | — | US | disclosed |
| CN-115397512-A | Pyridopyrimidinone derivatives as AHR antagonists | 先达生物科技公司 | 2022-11-25 | — | — | CN | disclosed |
| US-20170066742-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG-A SOCIO HOLDINGS CO LTD (KR) | 2017-03-09 | — | — | US | disclosed |
| WO-2017039331-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2017-03-09 | — | — | WO | disclosed |
| EP-1641887-B1 | CARBON-SUBSTITUTED METHYL AMINE DERIVATIVES AND THEIR USE AS A RHEOLOGY CONTROL AGENT | NUPLEX RESINS BV (NL) | 2010-10-06 | — | — | EP | disclosed |
| US-7671068-B2 | N-(alkoxyalkyl) carbamoyl-substituted 6-phenyl-benzonaphthyridine derivatives and their use as PDE ¾ inhibitors | NYCOMED GMBH (DE) | 2010-03-02 | — | — | US | disclosed |
| US-20090012071-A1 | 4-SUBSTITUTED-1H-ISOTHIAZOLO[5,4-B][1,4]OXAZINO[2,3,4-IJ]QUINOLINE-7,8(2H,9H)-DIONES AND RELATED COMPOUNDS AS ANTI-INFECTIVE AGENTS | ACHILLION PHARMACEUTICALS, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| US-20070208051-A1 | Novel N-(Alkoxyalkyl) Carbamoyl-Substituted 6-Phenyl-Benzonaphthyridine Derivatives and their Use as Pde 3/4 Inhibitors | ALTANA PHARMA AG (DE) | 2007-09-06 | — | — | US | disclosed |
| EP-1732925-A1 | NOVEL N-(ALKOXYALKYL)CARBAMOYL- SUBSTITUTED 6-PHENYL-BENZONAPHTHYRIDINE DERIVATIVES AND THEIR USE AS PDE3/4 INHIBITORS | Altana Pharma AG (DE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005090345-A1 | NOVEL N- (ALKOXYALKYL) CARBAMOYL - SUBSTITUTED 6-PHENYL-BENZONAPHTHYRIDINE DERIVATIVES AND THEIR USE AS PDE3/4 INHIBITORS | ALTANA PHARMA AG (DE) | 2005-09-29 | — | — | WO | disclosed |
| EP-0877815-A1 | METHOD OF PRODUCING OPTICALLY ACTIVE AMINES | BAYER AG (DE) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997028271-A1 | METHOD OF PRODUCING OPTICALLY ACTIVE AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295152-A1 | PYRIDOPYRIMIDINONE DERIVATIVES AS AHR ANTAGONISTS | AHR, ARNT, AIPL1 | TACR1 1288/4885TSHR 1109/4885SLC6A2 4616/4885 |
| US-12195446-B2 | Heteroaryl compounds and their use as therapeutic drugs | MERTK, ERBB2, SRC | TACR1 801/4885TSHR 1878/4885SLC6A2 1378/4885 |
| US-20090012071-A1 | 4-SUBSTITUTED-1H-ISOTHIAZOLO[5,4-B][1,4]OXAZINO[2,3,4-IJ]QUINOLINE-7,8(2H,9H)-DIONES AND RELATED COMPOUNDS AS ANTI-INFECTIVE AGENTS | TOP1, TOP2B, TOP2A | TACR1 3811/4885TSHR 4685/4885SLC6A2 3343/4885 |
| US-20260085067-A1 | CYCLIC SULFONAMIDE RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF | RRM1, RRM2B, RRM2 | TACR1 260/4885TSHR 76/4885SLC6A2 880/4885 |
| US-20070208051-A1 | Novel N-(Alkoxyalkyl) Carbamoyl-Substituted 6-Phenyl-Benzonaphthyridine Derivatives and their Use as Pde 3/4 Inhibitors | PDE3A, PDE4A, PDE5A | TACR1 734/4885TSHR 1788/4885SLC6A2 902/4885 |
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | MERTK, ERBB2, SRC | TACR1 801/4885TSHR 1878/4885SLC6A2 1378/4885 |
| US-20240294565-A1 | UNNATURAL CONFIGURATION NUCLEOTIDE PRODRUG COMPOUNDS | PNP, NUDT1, ENTPD5 | TACR1 1886/4885TSHR 3979/4885SLC6A2 822/4885 |
| US-20170066742-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | MERTK, ERBB2, SRC | TACR1 801/4885TSHR 1878/4885SLC6A2 1378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.