Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.51 |
| ▸ | PTPRC | P08575 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830890 | 0.72 | ALDH1A1 (0.53) | MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6412872 | 0.72 | S100A4 (0.58) | S100A4PTPRCCYP1A2MAPTCDC25B | |
| SCHEMBL19835545 | 0.70 | SLC6A3 (0.51) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL2599222 | 0.69 | S100A4 (1.00) | S100A4MAPK1CYP1A2TP53CYP2C9 | |
| SCHEMBL4995737 | 0.69 | MAPK1 (0.50) | MAPK1CYP1A2MAPTGAARECQL | |
| SCHEMBL23530100 | 0.68 | MKNK2 (0.39) | MAPK1CYP1A2MAPTGAARECQL | |
| SCHEMBL30791992 | 0.68 | MKNK2 (0.39) | MAPK1CYP1A2MAPTGAARECQL | |
| SCHEMBL69653 | 0.68 | MAPT (0.64) | CYP1A2MAPTGAARECQLNPC1 | |
| SCHEMBL1456298 | 0.67 | MAPK1 (0.57) | MAPK1MAPTTP53KDM4EL3MBTL1 | |
| SCHEMBL29442775 | 0.67 | MAPK1 (0.57) | MAPK1MAPTTP53KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807668-B2 | Anti-inflammatory compounds | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2010-10-05 | — | — | US | disclosed |
| US-20070265253-A1 | Anti-Inflammatory Compounds | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2007-11-15 | — | — | US | disclosed |
| EP-1789422-A1 | ANTI-INFLAMMATORY COMPOUNDS | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006031134-A1 | ANTI-INFLAMMATORY COMPOUNDS | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265253-A1 | Anti-Inflammatory Compounds | TNF, PTGS1, PTGES | S100A4 64/4885PTPRC 3605/4885MAPK1 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.