Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3557395 | 0.91 | REN (0.32) | REN | |
| SCHEMBL4646776 | 0.87 | REN (0.34) | ALDH1A1CYP3A4CYP2D6THRBCYP2C19 | |
| SCHEMBL2923347 | 0.87 | LMNA (0.36) | ALDH1A1 | |
| SCHEMBL2917973 | 0.83 | TMEM97 (0.35) | ALDH1A1REN | |
| SCHEMBL2919675 | 0.83 | CYP2C9 (0.35) | REN | |
| SCHEMBL5508707 | 0.83 | FKBP1A (0.36) | ALDH1A1 | |
| SCHEMBL2924197 | 0.83 | FKBP1A (0.36) | ALDH1A1 | |
| SCHEMBL3561383 | 0.82 | REN (0.30) | REN | |
| SCHEMBL4958115 | 0.82 | REN (0.35) | ALDH1A1CYP3A4CYP2D6THRBCYP2C19 | |
| SCHEMBL2915001 | 0.82 | FKBP1A (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687495-B2 | Substituted piperidines | SPEEDEL EXPERIMENTA AG (CH) | 2010-03-30 | — | — | US | disclosed |
| US-20080171748-A1 | Substituted piperidines | NOVARTIS AG (CH) | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171748-A1 | Substituted piperidines | REN, ACE, AGTR2 | ALDH1A1 222/4885CYP3A4 148/4885CYP2D6 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.