Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL584478 | 0.89 | TSHR (0.61) | TSHRL3MBTL1CHIT1PDK1PDK2 | |
| Trifluoroacetic Acid SCHEMBL9333894 | 0.89 | TSHR (0.61) | TSHRL3MBTL1CHIT1PDK1PDK2 | |
| Trifluoroacetic Acid SCHEMBL29059043 | 0.74 | NPC1 (0.44) | TSHRCHIT1HSD17B10TP53SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL27939406 | 0.74 | ALOX5 (0.48) | TSHRCHIT1PDK1PDK2PDK3 | |
| Trifluoroacetic Acid SCHEMBL584210 | 0.74 | MAPT (0.49) | L3MBTL1CES1HDAC1HDAC7HDAC8 | |
| Trichloroacetic Acid SCHEMBL3973964 | 0.74 | TSHR (0.61) | TSHRPDK1PDK2PDK3PDK4 | |
| Trifluoroacetic Acid SCHEMBL11500234 | 0.73 | CHIT1 (0.42) | TSHRCHIT1PDK1PDK2PDK3 | |
| Diphenylamine SCHEMBL31175857 | 0.73 | HSD17B10 (0.57) | TSHRL3MBTL1CES1HSD17B10PAX8 | |
| Trifluoroacetic Acid SCHEMBL21177989 | 0.73 | EPHX2 (0.46) | TSHRTP53EPHX2SMN1; SMN2MEN1 | |
| Trifluoroacetic Acid SCHEMBL28860217 | 0.73 | TRPV1 (0.47) | TSHRHSD17B10HDAC1HDAC7HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696356-B2 | Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one and ondansetron therefrom | TARO PHARMACEUTICAL INDUSTRIES LIMITED (IL) | 2010-04-13 | — | — | US | disclosed |
| US-20060041004-A1 | Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one and ondansetron therefrom | TARO PHARMACEUTICAL INDUSTRIES LIMITED (IL) | 2006-02-23 | — | — | US | disclosed |
| WO-2006018846-A2 | PROCESS FOR PREPARING 1,2,3,9-TETRAHYDRO-9-METHYL-3-METHYLENE-4H- CARBAZOL-4-ONE AND ONDANSETRON THEREFROM | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2006-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060041004-A1 | Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one and ondansetron therefrom | HTR3A, ADORA3, HTR4 | TSHR 2289/4885L3MBTL1 4367/4885CHIT1 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.