SCHEMBL3563847

SCHEMBL3563847

O=S(=O)(c1ccccc1)n1c(-c2ccccc2)c(O)c2cc(Cl)ccc21

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACLY P53396 11/20 0.58
SRC P12931 2/20 0.47
HTR6 P50406 2/20 0.47
PPARG P37231 3/20 0.46
PPARA Q07869 3/20 0.46
PPARD Q03181 2/20 0.46
AGTR1 P30556 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6421393 0.92 ACLY (0.53) ACLYHTR6AGTR1
SCHEMBL6423753 0.92 ACLY (0.59) ACLYHTR6PPARGPPARDAGTR1
SCHEMBL3562443 0.84 ACLY (0.50) ACLYSRCHTR6AGTR1
SCHEMBL3564623 0.84 PTGDR2 (0.54) ACLYSRCHTR6AGTR1
SCHEMBL3562959 0.84 AGTR1 (0.57) ACLYSRCHTR6PPARGPPARA
SCHEMBL3557485 0.83 AGTR1 (0.58) ACLYSRCHTR6AGTR1
SCHEMBL3565477 0.83 ACLY (0.57) ACLYSRCHTR6PPARGPPARA
SCHEMBL3558533 0.81 HTR6 (0.54) ACLYSRCHTR6AGTR1
SCHEMBL29839883 0.79 ACLY (0.64) ACLYHTR6PPARGPPARDAGTR1
SCHEMBL28409032 0.78 ACLY (0.57) ACLYHTR6PPARGPPARDAGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1567492-B1 N-ARYLSULFONYL-3-AMINOALKOXYINDOLES SUVEN LIFE SCIENCES LTD (IN) 2013-05-22 EP disclosed
US-7718690-B2 N-arylsulfonyl-3-aminoalkoxyindoles RAMAKRISHNA VENKATA SATYA NIROGI 2010-05-18 US disclosed
US-20090131507-A1 N-arylsulfonyl-3-aminoalkoxyindoles SUVEN LIFE SCIENCES LIMITED (IN) 2009-05-21 US disclosed
CN-1720227-A N-arylsulfonyl-3-aminoalkoxyindoles SUVEN LIFE SCIENCES LTD (IN) 2006-01-11 CN disclosed
EP-1567492-A2 N-ARYLSULFONYL-3-AMINOALKOXYINDOLES Suven Life Sciences Limited (IN) 2005-08-31 EP disclosed
WO-2004048328-A2 N-ARYLSULFONYL-3-AMINOALKOXYINDOLES SUVEN LIFE SCIENCES LIMITED (IN) 2004-06-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131507-A1 N-arylsulfonyl-3-aminoalkoxyindoles HTR3C, HTR3A, AANAT ACLY 4542/4885SRC 158/4885HTR6 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.