Pyruvate

Pyruvate

SCHEMBL356399

CC(=O)C(=O)[O-].C[N+](C)(C)C

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 3/20 0.77
CA1 P00915 2/20 0.50
TSHR P16473 2/20 0.43
THPO P40225 1/20 0.43
FAHD1 Q6P587 1/20 0.40
BLM P54132 2/20 0.37
THRB P10828 1/20 0.37
PMP22 Q01453 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
LMNA P02545 1/20 0.36
MEN1 O00255 1/20 0.33
LDHA P00338 1/20 0.33
KMT2A Q03164 1/20 0.33
FFAR3 O14843 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyruvate SCHEMBL148220 0.88
Pyruvate SCHEMBL3745552 0.84 CA4 (0.91) CA4CA1TSHRTHPOFAHD1
Pyruvate SCHEMBL1331761 0.84
Pyruvate SCHEMBL1332958 0.84
Pyruvate SCHEMBL1332703 0.84
Pyruvate SCHEMBL7936306 0.84 CA4 (0.91) CA4CA1TSHRTHPOFAHD1
Pyruvate SCHEMBL6743471 0.84 CA4 (0.91) CA4CA1TSHRTHPOFAHD1
Pyruvate SCHEMBL18226 0.84
Pyruvate SCHEMBL597153 0.84 CA4 (0.91) CA4CA1TSHRTHPOFAHD1
Pyruvate SCHEMBL597752 0.84 CA4 (0.91) CA4CA1TSHRTHPOFAHD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2414476-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. du Pont de Nemours and Company (US) 2012-02-08 EP claimed
US-20120011886-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY 2012-01-19 US claimed
WO-2010117836-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-10-14 WO claimed
EP-2414476-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. du Pont de Nemours and Company (US) 2012-02-08 EP disclosed
US-20120011886-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY 2012-01-19 US disclosed
WO-2010117836-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-10-14 WO disclosed