SCHEMBL3055313

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4436990	0.84	ALDH1A1 (0.50)	ALDH1A1MAPTLMNASMN1; SMN2KDM4E
	SCHEMBL28080918	0.81	ACHE (0.59)	ALDH1A1MAPTLMNASMN1; SMN2KDM4E
	SCHEMBL20681622	0.79	KDM4E (0.62)	ALDH1A1MAPTLMNASMN1; SMN2KDM4E
	SCHEMBL356412	0.78	KDM4E (0.59)	ALDH1A1MAPTSMN1; SMN2KDM4EGAA
	SCHEMBL8202942	0.77	ALDH1A1 (0.50)	ALDH1A1MAPTLMNASMN1; SMN2KDM4E
	SCHEMBL2713576	0.77	NPC1 (0.52)	ALDH1A1MAPTLMNASMN1; SMN2KDM4E
	SCHEMBL2714767	0.77	TTR (0.53)	ALDH1A1MAPTLMNASMN1; SMN2KDM4E
	SCHEMBL4550723	0.77	KDM4E (0.49)	ALDH1A1MAPTLMNASMN1; SMN2KDM4E
	SCHEMBL27090	0.77	CA2 (0.54)	ALDH1A1KDM4EGAACYP1A2TSHR
	SCHEMBL16954400	0.77	PDE4B (0.46)	ALDH1A1MAPTLMNASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.