Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 3/20 | 0.36 |
| ▸ | GABRD | O14764 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956728 | 1.00 | KDM4E (0.44) | KDM4EALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL28170830 | 0.83 | NNMT (0.41) | KDM4EALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL7456714 | 0.76 | ALDH1A1 (0.50) | KDM4EALDH1A1MAPTL3MBTL1KDM4C | |
| SCHEMBL68960 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL30978924 | 0.76 | HCAR2 (0.44) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL352483 | 0.76 | SPR (0.45) | KDM4EALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL629032 | 0.76 | HCAR2 (0.44) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL758324 | 0.74 | NAPRT (0.48) | KDM4EALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL9278316 | 0.74 | MEN1 (0.46) | KDM4EALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL20928646 | 0.74 | HCAR2 (0.43) | KDM4EALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107176926-A | A kind of preparation method of pyridine derivatives | 湖南华腾制药有限公司 | 2017-09-19 | — | — | CN | claimed |
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| WO-2025091127-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | UNIVERSITE DE MONTREAL (CA) | 2025-05-08 | — | — | WO | disclosed |
| CN-111118482-A | Chemical silver plating solution and application | 深圳市正天伟科技有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-109956942-A | Tryptamines ketones derivant and application thereof | 上海翔锦生物科技有限公司 | 2019-07-02 | — | — | CN | disclosed |
| CN-109322145-A | Crease-resistant elastic force breathable fabric | 潢川县圣宇服饰科技有限公司 | 2019-02-12 | — | — | CN | disclosed |
| EP-2580207-B1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2017-09-27 | — | — | EP | disclosed |
| CN-107176926-A | A kind of preparation method of pyridine derivatives | 湖南华腾制药有限公司 | 2017-09-19 | — | — | CN | disclosed |
| CN-107176926-A | A kind of preparation method of pyridine derivatives | 湖南华腾制药有限公司 | 2017-09-19 | — | — | CN | disclosed |
| CN-102947292-B | nitrogen-containing heteroaryl compounds | HOFFMAN-LA ROCHE LTD. (CH) | 2015-08-19 | — | — | CN | disclosed |
| US-8703768-B2 | Nitrogen containing heteroaryl compounds | HOFFMANN-LA ROCHE INC. (US) | 2014-04-22 | — | — | US | disclosed |
| US-20070219261-A1 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. | 2007-09-20 | — | — | US | disclosed |
| CN-1319969-C | Fungicides | SYNGENTA LTD (GB) | 2007-06-06 | — | — | CN | disclosed |
| EP-1513820-A4 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2006-09-13 | — | — | EP | disclosed |
| US-20060111374-A1 | Compounds, compositions, and methods | CYTOKINETICS, INC. | 2006-05-25 | — | — | US | disclosed |
| US-7038048-B2 | 3H-pyridopyrimidin-4-one compounds, compositions, and methods of their use | CYTOKINETICS, INC. (US) | 2006-05-02 | — | — | US | disclosed |
| CN-1732170-A | Fungicidal agents | SYNGENTA LTD (GB) | 2006-02-08 | — | — | CN | disclosed |
| EP-1513820-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2005-03-16 | — | — | EP | disclosed |
| US-20040116438-A1 | Compounds, compositions, and methods | CYTOKINETICS, INCORPORATED | 2004-06-17 | — | — | US | disclosed |
| WO-2003103575-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111374-A1 | Compounds, compositions, and methods | ALPP, MKI67, PCNA | KDM4E 1421/4885ALDH1A1 2342/4885TDP1 1140/4885 |
| US-20070219261-A1 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | AADAT, AAAS, AADAC | KDM4E 1828/4885ALDH1A1 1414/4885TDP1 3535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.