Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461137 | 0.85 | ALDH1A1 (0.36) | KDM4EMAPTALDH1A1LMNATSPO | |
| SCHEMBL7601778 | 0.84 | TP53 (0.35) | KDM4EALDH1A1LMNASMN1; SMN2TSPO | |
| SCHEMBL8179754 | 0.83 | ATM (0.41) | L3MBTL1ALDH1A1SMN1; SMN2TSPOTDP1 | |
| SCHEMBL7602423 | 0.83 | KDM4E (0.33) | CES2CES1KDM4EALDH1A1LMNA | |
| SCHEMBL7601779 | 0.83 | CYP2C19 (0.33) | CES2CES1KDM4EALDH1A1LMNA | |
| SCHEMBL4510192 | 0.77 | ALDH1A1 (0.38) | CES2CES1KDM4EMAPTALDH1A1 | |
| SCHEMBL8779737 | 0.75 | TRPM8 (0.46) | KDM4EALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL8636800 | 0.75 | ALDH1A1 (0.34) | KDM4EALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL6700583 | 0.75 | TSHR (0.46) | KDM4EL3MBTL1ALDH1A1LMNATSHR | |
| SCHEMBL8614764 | 0.75 | ALDH1A1 (0.44) | CES2CES1KDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845086-B1 | N-(2-substituted phenyl)-N-methoxycarbamates and their preparation and use thereof | SHENYANG RES INST CHEMICAL IND (CN) | 2013-04-24 | — | — | EP | disclosed |
| US-7666884-B2 | N-(2-substituted phenyl)-N-methoxycarbamates and their preparation and use thereof | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2010-02-23 | — | — | US | disclosed |
| US-20090048309-A1 | N-(2-SUBSTITUTED PHENYL)-N-METHOXYCARBAMATES AND THEIR PREPARATION AND USE THEREOF | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2009-02-19 | — | — | US | disclosed |
| EP-1845086-A1 | N-(2-SUBSTITUTED PHENYL)-N-METHOXYCARBAMATES AND THEIR PREPARATION AS WELL AS USE | Shenyang Research Institute of Chemical Industry (CN) | 2007-10-17 | — | — | EP | disclosed |
| EP-1070052-A1 | FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP | AVENTIS CROPSCIENCE S.A. (FR) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999051579-A1 | FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP | AVENTIS CROPSCIENCE S.A. (FR) | 1999-10-14 | — | — | WO | disclosed |
| WO-1999033813-A1 | 3-HYDROXY-PYRAZOLE FUNGICIDAL DERIVATIVES | AVENTIS CROPSCIENCE S.A.; (FR) | 1999-07-08 | — | — | WO | disclosed |
| WO-1999033812-A1 | 3-(5)-BENZYLOXYPYRAZOLE USEFUL AS FUNGICIDES | AVENTIS CROPSCIENCE S.A. (FR) | 1999-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048309-A1 | N-(2-SUBSTITUTED PHENYL)-N-METHOXYCARBAMATES AND THEIR PREPARATION AND USE THEREOF | MANBA, BAK1, BROX | CES2 2305/4885CES1 1714/4885KDM4E 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.