Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210492 | 0.86 | PTPN1 (0.38) | ALDH1A1KDM4ENPC1RAB9ACA12 | |
| SCHEMBL8751654 | 0.85 | LMNA (0.43) | ALDH1A1KDM4ENPC1RAB9ACA12 | |
| SCHEMBL8885290 | 0.84 | HSD11B1 (0.44) | ALDH1A1KDM4ENPC1RAB9ATP53 | |
| SCHEMBL7705866 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4ENPC1RAB9ACA12 | |
| SCHEMBL9142099 | 0.83 | PTPN1 (0.37) | ALDH1A1KDM4ENPC1RAB9ACA12 | |
| SCHEMBL7643329 | 0.82 | GABRA1 (0.44) | ALDH1A1KDM4ENPC1RAB9AHPGD | |
| SCHEMBL28272164 | 0.81 | TSPO (0.37) | ALDH1A1TP53GAAMAPTTSHR | |
| Hydrochloric Acid SCHEMBL17258978 | 0.80 | KDM4E (0.37) | ALDH1A1KDM4ENPC1RAB9ACA12 | |
| Ethane SCHEMBL11477742 | 0.80 | ALDH1A1 (0.37) | ALDH1A1KDM4ENPC1RAB9ACA12 | |
| SCHEMBL9049204 | 0.80 | POLQ (0.39) | ALDH1A1KDM4ETP53GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1864971-A1 | PROPHYLACTIC/THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2007-12-12 | — | — | EP | disclosed |
| CN-86108691-A | Pyrazole oxime derivatives, process for their preparation and their use | NIHON NOHYAKU CO LTD (JP) | 1988-01-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | ALDH1A1 51/4885KDM4E 2703/4885NPC1 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.