Sugi Predict

Sugi Predict / Compounds / SCHEMBL3569008

SCHEMBL3569008

SCHEMBL3569008

O=C(Cl)c1ccnc(F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TAS1R3 Q7RTX0 1/20 0.44
▸ TAS1R1 Q7RTX1 1/20 0.44
▸ TAS1R2 Q8TE23 1/20 0.44
▸ PFKFB3 Q16875 1/20 0.42
▸ BRAF P15056 1/20 0.40
▸ ALDH1A1 P00352 3/20 0.39
▸ KDM4E B2RXH2 3/20 0.39
▸ KDM4A O75164 3/20 0.39
▸ KDM4C Q9H3R0 3/20 0.39
▸ KDM6B O15054 2/20 0.39
▸ KDM5C P41229 2/20 0.39
▸ KDM2A Q9Y2K7 2/20 0.39
▸ KDM3A Q9Y4C1 2/20 0.39
▸ KDM5A P29375 2/20 0.39
▸ ASPH Q12797 2/20 0.39
▸ KDM8 Q8N371 2/20 0.39
▸ KDM5B Q9UGL1 2/20 0.39
▸ TET3 O43151 1/20 0.39
▸ BBOX1 O75936 1/20 0.39
▸ MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957382 0.81 KDM4C (0.61) TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E
SCHEMBL118817 0.81 KDM4C (0.61) TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL28045024 0.79 KDM4C (0.59) TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E
SCHEMBL29967026 0.79 TAS1R3 (0.48) TAS1R3TAS1R1TAS1R2PFKFB3BRAF
SCHEMBL1437180 0.79 TAS1R3 (0.48) TAS1R3TAS1R1TAS1R2PFKFB3BRAF
SCHEMBL2996754 0.79 PARP1 (0.48) TAS1R3TAS1R1TAS1R2PFKFB3BRAF
SCHEMBL3194722 0.78 KDM5C (0.53) ALDH1A1KDM4EKDM4AKDM4CKDM6B
SCHEMBL73194 0.77 TAS1R3 (0.45) TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E
SCHEMBL30182299 0.77 ALDH1A1 (0.55) ALDH1A1KDM4EKDM4AKDM4CKDM6B
SCHEMBL27733457 0.77 KDM4C (0.41) ALDH1A1KDM4EKDM4AKDM4CKDM6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63130582-A — — None — — JP disclosed
EP-4725942-A1 COMPOUNDS ACTIVE ON CYCLIN D1 PATHWAY AND THEIR USE Sibylla Biotech S.p.A. (IT) 2026-04-15 — — EP disclosed
EP-4041732-B1 ISO-CITRATE DEHYDROGENASE (IDH) INHIBITOR ZHEJIANG METON PHARMACEUTICAL CO LTD (CN) 2026-03-18 — — EP disclosed
US-12441725-B2 ISO-citrate dehydrogenase (IDH) inhibitor ZHEJIANG METON PHARMACEUTICAL CO., LTD (CN) 2025-10-14 — — US disclosed
US-20250230157-A1 AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS RAPPORT THERAPEUTICS, INC. 2025-07-17 — — US disclosed
US-12304908-B2 Azabenzimidazoles and their use as AMPA receptor modulators RAPPORT THERAPEUTICS, INC. (US) 2025-05-20 — — US disclosed
US-12145934-B2 Azabenzimidazoles and their use as AMPA receptor modulators JANSSEN PHARMACEUTICA NV (BE) 2024-11-19 — — US disclosed
US-12139485-B2 Azabenzimidazoles and their use as AMPA receptor modulators JANSSEN PHARMACEUTICA NV (BE) 2024-11-12 — — US disclosed
US-20240270762-A1 PENICILLIN-BINDING PROTEIN INHIBITORS SPRING MILL PHARMA, INC. 2024-08-15 — — US disclosed
CN-114555597-B Isocitrate Dehydrogenase (IDH) inhibitors 浙江迈同生物医药有限公司 2024-06-04 — — CN disclosed
EP-1250340-A1 METHODS AND COMPOUNDS FOR INHIBITING MRP1 ELI LILLY AND COMPANY (US) 2002-10-23 — — EP disclosed
WO-2002024705-A1 STEREOSELECTIVE PROCESS FOR PREPARING CYCLOHEXYL AMINE DERIVATIVES ELI LILLY AND COMPANY (US) 2002-03-28 — — WO disclosed
WO-2001046199-A1 METHODS AND COMPOUNDS FOR INHIBITING MRP1 ELI LILLY AND COMPANY (US) 2001-06-28 — — WO disclosed
US-5583148-A FUNGICIDE, BACTERICIDE AND ANTICARCINOGENIC AGENT RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1996-12-10 — — US disclosed
EP-0479951-A4 BIS-ACYLOXYMETHYL DERIVATIVES — 1992-12-09 — — EP disclosed
EP-0479951-A1 BIS-ACYLOXYMETHYL DERIVATIVES THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1992-04-15 — — EP disclosed
WO-1991000093-A1 BIS-ACYLOXYMETHYL DERIVATIVES THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1991-01-10 — — WO disclosed
US-4804762-A FUNGICIDES, BACTERICIDES NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1989-02-14 — — US disclosed
JP-S63130582-A N-CYANOMETHYLISONICONITIC ACID AMIDE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE CONTAINING SAME NIPPON KAYAKU CO LTD 1988-06-02 — — JP disclosed
EP-0246507-A1 N-cyanoalkylisonicotinamide derivatives NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1987-11-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12139485-B2 Azabenzimidazoles and their use as AMPA receptor modulators GRIN1, GRIN2B, GRIN3A TAS1R3 670/4885TAS1R1 459/4885TAS1R2 557/4885
US-12145934-B2 Azabenzimidazoles and their use as AMPA receptor modulators GRIN1, GRIN2B, GRIN3A TAS1R3 670/4885TAS1R1 459/4885TAS1R2 557/4885
US-20240270762-A1 PENICILLIN-BINDING PROTEIN INHIBITORS PEPD, BPGM, EBPL TAS1R3 2400/4885TAS1R1 2090/4885TAS1R2 2564/4885
US-12304908-B2 Azabenzimidazoles and their use as AMPA receptor modulators GRIN1, GRIN2B, GRIN3A TAS1R3 670/4885TAS1R1 459/4885TAS1R2 557/4885
US-20250230157-A1 AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS GRIN1, GRIN2B, GRIN3A TAS1R3 678/4885TAS1R1 438/4885TAS1R2 537/4885
US-12441725-B2 ISO-citrate dehydrogenase (IDH) inhibitor IDH2, IDH3A, IDH1 TAS1R3 4080/4885TAS1R1 4031/4885TAS1R2 3797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.