Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29685513 | 1.00 | MTNR1A (0.47) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL31596506 | 0.81 | MTNR1A (0.50) | MTNR1AMTNR1BKMT2AKDM4EGAA | |
| SCHEMBL28853339 | 0.81 | MTNR1A (0.40) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL905742 | 0.80 | ALDH1A1 (0.49) | MTNR1AMTNR1BKDM4ELMNATSHR | |
| SCHEMBL22717888 | 0.79 | KDM4E (0.45) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL905702 | 0.78 | MTNR1A (0.43) | MTNR1AMTNR1BKMT2AMEN1GAA | |
| SCHEMBL17846702 | 0.78 | MTNR1A (0.43) | MTNR1AMTNR1BKDM4ETSHRALDH1A1 | |
| SCHEMBL25780533 | 0.78 | SLC6A3 (0.41) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL25780555 | 0.78 | SLC6A3 (0.44) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL27698463 | 0.77 | ALDH1A1 (0.43) | MTNR1AMTNR1BKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260180-B | Triazole condensed ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-115260180-A | Triazole fused ring containing derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-01 | — | — | CN | disclosed |
| US-20210395242-A1 | HETEROCYCLIC COMPOUNDS AS AHR MODULATORS | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2021-12-23 | — | — | US | disclosed |
| WO-2020043880-A1 | HETEROCYCLIC COMPOUNDS AS AHR MODULATORS | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2020-03-05 | — | — | WO | disclosed |
| CN-105392498-A | Anti-malignant tumor agent composition | PHARMA CO LTD J | 2016-03-09 | — | — | CN | disclosed |
| CN-101910158-A | Pyridine and pyrazine derivatives useful in the treatment of cell proliferative disorders | ASTRAZENECA AB | 2010-12-08 | — | — | CN | disclosed |
| US-7645753-B2 | Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2010-01-12 | — | — | US | disclosed |
| EP-1858901-B1 | BENZOTHIAZOLE, THIAZOLOPYRIDINE, BENZOOXAZOLE AND OXAZOLOPYRIDINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2008-11-05 | — | — | EP | disclosed |
| CN-101160307-A | Benzoxazole carboxamides for the treatment of CINV and IBS-D | AMR TECHNOLOGY INC (US) | 2008-04-09 | — | — | CN | disclosed |
| EP-1858901-A1 | BENZOTHIAZOLE, THIAZOLOPYRIDINE, BENZOOXAZOLE AND OXAZOLOPYRIDINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2007-11-28 | — | — | EP | disclosed |
| CN-1293042-C | Aromatic amino acid derivative and pharmaceutical composition thereof | HITOSHI ENDOU (JP) | 2007-01-03 | — | — | CN | disclosed |
| WO-2006094682-A1 | BENZOTHIAZOLE, THIAZOLOPYRIDINE, BENZOOXAZOLE AND OXAZOLOPYRIDINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-09-14 | — | — | WO | disclosed |
| US-20060205718-A1 | Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2006-09-14 | — | — | US | disclosed |
| CN-1630632-A | Aromatic amino acid derivative and pharmaceutical composition thereof | HITOSHI ENDOU (JP) | 2005-06-22 | — | — | CN | disclosed |
| CN-1039904-C | Herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-09-23 | — | — | CN | disclosed |
| CN-1104212-A | Herbicides | RHONE POULENC AGRICULTURE (GB) | 1995-06-28 | — | — | CN | disclosed |
| CN-1095379-A | Condensed heterocyclic derivates and weedicide | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1994-11-23 | — | — | CN | disclosed |
| US-5200420-A | Inotropic agents for cardiovascular disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395242-A1 | HETEROCYCLIC COMPOUNDS AS AHR MODULATORS | AHR, ARNT, AIPL1 | MTNR1A 244/4885MTNR1B 252/4885KMT2A 806/4885 |
| US-20060205718-A1 | Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives | SSTR5, SSTR1, SSTR2 | MTNR1A 257/4885MTNR1B 275/4885KMT2A 4113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.