SCHEMBL357401

SCHEMBL357401

C[C@H](NC(=O)OC(C)(C)C)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.42
GLA P06280 2/20 0.42
HPGD P15428 2/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
EPHX2 P34913 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
KMT2A Q03164 2/20 0.38
CA12 O43570 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CYP2D6 P10635 1/20 0.35
PREP P48147 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HTT P42858 1/20 0.35
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34
CTSK P43235 1/20 0.34
GLS O94925 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6890388 1.00 KDM4E (0.42) KDM4EGLAHPGDGAAMAPT
SCHEMBL356359 1.00 KDM4E (0.42) KDM4EGLAHPGDGAAMAPT
SCHEMBL12432342 0.95 KMT2A (0.40) KDM4EGLAHPGDGAAMAPT
SCHEMBL29484192 0.95 KMT2A (0.40) KDM4EGLAHPGDGAAMAPT
SCHEMBL18206532 0.91 KDM4E (0.38) KDM4EGLAHPGDGAAMAPT
SCHEMBL18206533 0.91 KDM4E (0.38) KDM4EGLAHPGDGAAMAPT
SCHEMBL18206529 0.91 KDM4E (0.38) KDM4EGLAHPGDGAAMAPT
SCHEMBL31587441 0.88 CTSK (0.45) KDM4EHPGDCA2KMT2APREP
SCHEMBL2580872 0.87 PREP (0.39) KDM4EHPGDCA1CA2CA7
SCHEMBL6159871 0.86 PREP (0.44) KDM4EHPGDCA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112060793-B Corrugated carton gradient color pattern flexible printing process 安徽美盈森智谷科技有限公司 2022-04-05 CN claimed
CN-112060793-A Corrugated carton gradient color pattern flexible printing process 安徽美盈森智谷科技有限公司 2020-12-11 CN claimed
US-12612420-B2 Arginase inhibitors and methods of use thereof MOLECURE S.A. (PL) 2026-04-28 US disclosed
EP-4087583-B1 ARGINASE INHIBITORS AND METHODS OF USE MERCK SHARP & DOHME LLC (US) 2026-04-22 EP disclosed
EP-4725560-A2 ANTI-B7H3 ANTIBODIES FOR THE PREPARATION OF ANTIBODY DRUG CONJUGATES (ADCS) OF KSP INHIBITORS Bayer Pharma Aktiengesellschaft (DE) 2026-04-15 EP disclosed
US-20260071353-A1 SUBSTRATES, PEPTIDE ARRAYS, AND METHODS VIBRANT HOLDINGS LLC (US) 2026-03-12 US disclosed
EP-3897622-B1 ARGINASE INHIBITORS AND METHODS OF USE MERCK SHARP & DOHME LLC (US) 2026-01-14 EP disclosed
EP-4673474-A2 ANTI-PSMA ANTIBODIES, CONJUGATES, AND METHODS OF USE Eisai R&D Management Co., Ltd. (JP) 2026-01-07 EP disclosed
US-12454771-B2 Substrates, peptide arrays, and methods VIBRANT HOLDINGS LLC (US) 2025-10-28 US disclosed
US-20250320233-A1 ARGINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DAEWOONG PHARMACEUTICAL CO LTD (KR) 2025-10-16 US disclosed
US-20250304563-A1 ACTIVATORS OF EFFECTOR T CELLS ORUM THERAPEUTICS, INC. (KR) 2025-10-02 US disclosed
US-4711879-A IMMUNO-MODULATING ACTIVITY CIBA-GEIGY CORPORATION (US) 1987-12-08 US disclosed
EP-0214659-A2 Peptide derivatives, process for the production thereof and pharmaceutical compositions containing same GREEN CROSS CORPORATION (JP) 1987-03-18 EP disclosed
US-4640911-A IMMUNOSTIMULANTS, VIRICIDES SUCH AS HERPES SIMPLEX CIBA-GEIGY CORPORATION (US) 1987-02-03 US disclosed
EP-0193904-A2 Amino acid derivatives and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-09-10 EP disclosed
EP-0192611-A2 Acylated hexose derivatives and method for their preparation CIBA-GEIGY AG (CH) 1986-08-27 EP disclosed
EP-0163286-A2 Acylated sugars, method for their preparation and their use CIBA-GEIGY AG (CH) 1985-12-04 EP disclosed
US-4548923-A IMMUNOSTIMULANTS, BACTERICIDES, VIRICIDES CIBA GEIGY CORPORATION (US) 1985-10-22 US disclosed
EP-0099578-A1 Muramyl peptides and method for their preparation CIBA-GEIGY AG (CH) 1984-02-01 EP disclosed
US-4299820-A CARDIOVASCULAR DISORDERS PFIZER INC. (US) 1981-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071353-A1 SUBSTRATES, PEPTIDE ARRAYS, AND METHODS VIP, CALCB, SPPL2B KDM4E 4396/4885GLA 4499/4885HPGD 4065/4885
US-20250304563-A1 ACTIVATORS OF EFFECTOR T CELLS CBLB, CBL, CBLC KDM4E 1344/4885GLA 2598/4885HPGD 4643/4885
US-20250320233-A1 ARGINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME ARG1, ARG2, PRMT1 KDM4E 1438/4885GLA 2937/4885HPGD 459/4885
US-12612420-B2 Arginase inhibitors and methods of use thereof ARG1, ARG2, ARGLU1 KDM4E 406/4885GLA 1454/4885HPGD 1682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.