SCHEMBL6159871

SCHEMBL6159871

CC(C)C(NC(=O)OC(C)(C)C)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PREP P48147 1/20 0.44
CTSK P43235 3/20 0.44
CTSS P25774 2/20 0.44
CTSL P07711 2/20 0.43
CTSB P07858 1/20 0.43
TRPA1 O75762 2/20 0.41
CA2 P00918 2/20 0.40
CA1 P00915 1/20 0.40
CA7 P43166 1/20 0.40
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
ELANE P08246 1/20 0.38
KLK5 Q9Y337 1/20 0.38
CYP2D6 P10635 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SRC P12931 1/20 0.36
PSENEN Q9NZ42 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7061312 1.00 PREP (0.44) PREPCTSKCTSSCTSLCTSB
SCHEMBL197689 1.00 PREP (0.44) PREPCTSKCTSSCTSLCTSB
SCHEMBL29484188 0.95 CTSK (0.46) PREPCTSKCTSSCTSLCTSB
SCHEMBL2580872 0.93 PREP (0.39) PREPCTSKCTSSCTSLCTSB
SCHEMBL721602 0.90 PREP (0.38) PREPCTSKCTSSCTSLCTSB
SCHEMBL31587441 0.89 CTSK (0.45) PREPCTSKCTSSCTSLCTSB
SCHEMBL11803999 0.87 CTSK (0.38) PREPCTSKCTSSCTSLCTSB
SCHEMBL4969025 0.87 CTSK (0.49) CTSKCTSSCTSLCTSBCA2
SCHEMBL5696168 0.87 CTSK (0.49) CTSKCTSSCTSLCTSBCA2
SCHEMBL23771884 0.86 CTSK (0.38) PREPCTSKCTSSCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113502230-B Hericium erinaceus strain and culture method thereof, hericium erinaceus-ginseng bidirectional solid fermentation method and method for efficiently converting rare ginsenoside 长春中医药大学 2023-07-04 CN claimed
US-11541091-B2 Panax plant extract and pharmaceutical composition and use thereof SHANGHAI HUIYU BIOMEDICAL TECHNOLOGY CO., LTD. (CN) 2023-01-03 US claimed
US-12485088-B2 Rapidly-orodispersible tablets having an interior cavity Aprecia Pharmaceuticals LLC (US) 2025-12-02 US disclosed
US-12324856-B2 Oral drug dosage form comprising drug in the form of nanoparticles Triastek, Inc. (CN) 2025-06-10 US disclosed
EP-4512394-A2 DOSAGE FORMS AND USE THEREOF Triastek, Inc. (CN) 2025-02-26 EP disclosed
EP-4171518-B1 RAPIDLY-ORODISPERSIBLE TABLETS HAVING AN INTERIOR CAVITY Aprecia Pharmaceuticals LLC (US) 2024-12-11 EP disclosed
US-20240342094-A1 COMPARTMENTED PHARMACEUTICAL DOSAGE FORMS Triastek, Inc. (CN) 2024-10-17 US disclosed
EP-3302442-B1 DOSAGE FORMS AND USE THEREOF TRIASTEK INC (CN) 2024-10-16 EP disclosed
US-12102721-B2 Dosage forms of controlled release at specific gastrointestinal sites Triastek, Inc. (CN) 2024-10-01 US disclosed
US-12042562-B2 3D printing methods for compartmented pharmaceutical dosage forms Triastek, Inc. (CN) 2024-07-23 US disclosed
US-11802110-B2 2-amino-N-(arylsulfinyl)-acetamide compounds as inhibitors of bacterial aminoacyl-tRNA synthetase Oxford Drug Design Limited (GB) 2023-10-31 US disclosed
EP-1372692-A4 ASYMMETRIC SYNTHESIS OF (S, S, R)-(-)-ACTINONIN AND ITS ANALOGS AND USES THEREFOR SLOAN KETTERING INST CANCER (US) 2005-10-26 EP disclosed
WO-2005095403-A2 MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION INTERMUNE, INC. (US) 2005-10-13 WO disclosed
US-6887887-B2 Asymmetric synthesis of (S,S,R)-(-)-actinonin and its analogs and uses therefor SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2005-05-03 US disclosed
WO-2005037214-A2 MACROCYCLIC CARBOXYLIC ACIDS AND ACYLSULFONAMIDES AS INHIBITORS OF HCV REPLICATION INTERMUNE, INC. (US) 2005-04-28 WO disclosed
US-20040019083-A1 Asymmetric synthesis of (S,S,R)-(-)-actinonin and its analogs and uses therefor SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH 2004-01-29 US disclosed
EP-1372692-A2 ASYMMETRIC SYNTHESIS OF (S, S, R)-(-)-ACTINONIN AND ITS ANALOGS AND USES THEREFOR Sloan Kettering Institute For Cancer Research (US) 2004-01-02 EP disclosed
US-6660741-B2 Coupling an O-protected methoxypyrrolidine or derivatives with N-protected amino acid 2,5-dioxo-pyrrolidinyl ester to form intermediate, deportecting with trifluoroacetic acid to form pyrrolidine-1-carbonyl-2-methylamine or derivatives SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH 2003-12-09 US disclosed
US-20020198156-A1 Asymmetric synthesis of (S,S,R)-(-)-actinonin and its analogs and uses therefor SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH 2002-12-26 US disclosed
WO-2002074050-A2 ASYMMETRIC SYNTHESIS OF (S, S, R)-(-)-ACTINONIN AND ITS ANALOGS AND USES THEREFOR SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2002-09-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020198156-A1 Asymmetric synthesis of (S,S,R)-(-)-actinonin and its analogs and uses therefor HASPIN, CYTH2, ACTR3 PREP 2103/4885CTSK 1424/4885CTSS 488/4885
US-11802110-B2 2-amino-N-(arylsulfinyl)-acetamide compounds as inhibitors of bacterial aminoacyl-tRNA synthetase AARS1, NSUN3, GARS1 PREP 873/4885CTSK 3008/4885CTSS 531/4885
US-12324856-B2 Oral drug dosage form comprising drug in the form of nanoparticles CYP2D6, CYP3A5, CYP3A7 PREP 3079/4885CTSK 1788/4885CTSS 1556/4885
US-20240342094-A1 COMPARTMENTED PHARMACEUTICAL DOSAGE FORMS CYP2D6, CYP3A5, CYP2F1 PREP 1266/4885CTSK 1191/4885CTSS 929/4885
US-11541091-B2 Panax plant extract and pharmaceutical composition and use thereof RXFP3, PCSK9, RXFP1 PREP 3400/4885CTSK 3625/4885CTSS 3420/4885
US-12042562-B2 3D printing methods for compartmented pharmaceutical dosage forms CYP3A43, HTR3D, CYP3A7 PREP 3176/4885CTSK 2116/4885CTSS 2065/4885
US-20040019083-A1 Asymmetric synthesis of (S,S,R)-(-)-actinonin and its analogs and uses therefor HASPIN, CYTH2, CYTH3 PREP 2043/4885CTSK 1319/4885CTSS 448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.