Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.37 |
| ▸ | MICA | Q29983 | 1/20 | 0.37 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 2/20 | 0.35 |
| ▸ | FLT1 | P17948 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | IL2 | P60568 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3572359 | 0.91 | TRPV1 (0.37) | TRPV1ROCK2RAF1ESRRGMAPK14 | |
| SCHEMBL3583321 | 0.87 | TRPV1 (0.42) | TRPV1HIF1AEPAS1 | |
| SCHEMBL3571051 | 0.83 | NR1H4 (0.37) | TRPV1ROCK2ESRRGESRRB | |
| SCHEMBL9957841 | 0.81 | ESRRG (0.39) | TRPV1SLC22A12ROCK2RAF1ESRRG | |
| SCHEMBL3577133 | 0.80 | CYP51A1 (0.36) | TRPV1ROCK2RPS6KB1ESRRGESRRB | |
| SCHEMBL3583632 | 0.78 | RAF1 (0.37) | RAF1AURKARPS6KB1KDR | |
| SCHEMBL12520972 | 0.77 | TRPM8 (0.37) | ESRRGESRRB | |
| SCHEMBL3574429 | 0.77 | KDM4C (0.39) | TRPV1ROCK2ESRRGESRRB | |
| SCHEMBL3578904 | 0.76 | LMNA (0.44) | MEN1KMT2A | |
| SCHEMBL3576126 | 0.75 | CYP2C19 (0.37) | TRPV1SLC22A12ROCK2ESRRGESRRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |