Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580876 | 0.89 | LPAR1 (0.36) | PPARAPPARDPPARGALDH1A1FABP2 | |
| SCHEMBL3578978 | 0.87 | CNR1 (0.43) | SMN1; SMN2LPAR1LPAR5C5AR1RCE1 | |
| SCHEMBL3583296 | 0.86 | LPAR1 (0.52) | LPAR1LPAR5C5AR1RCE1 | |
| SCHEMBL3577662 | 0.84 | LPAR1 (0.43) | PPARAPPARDPPARGALDH1A1FABP2 | |
| SCHEMBL3583039 | 0.84 | CNR1 (0.43) | SMN1; SMN2C5AR1RCE1 | |
| SCHEMBL3577052 | 0.83 | C5AR1 (0.37) | ALDH1A1SMN1; SMN2LPAR1LPAR5C5AR1 | |
| SCHEMBL3576227 | 0.80 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2LPAR1LPAR5C5AR1 | |
| SCHEMBL3579938 | 0.80 | MAPT (0.42) | SMN1; SMN2LPAR1LPAR5KDM4ERCE1 | |
| SCHEMBL3577563 | 0.79 | NLRP3 (0.42) | PPARAPPARDPPARGALDH1A1LPAR1 | |
| SCHEMBL3574141 | 0.77 | LPAR1 (0.41) | PPARAPPARDPPARGALDH1A1FABP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |