Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 15/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361173 | 0.97 | PARP1 (0.41) | PARP1UCHL1MEN1KMT2AUSP30 | |
| SCHEMBL359451 | 0.83 | PARP1 (0.51) | PARP1USP30 | |
| SCHEMBL359239 | 0.82 | PARP1 (0.51) | PARP1 | |
| SCHEMBL359388 | 0.81 | PARP1 (0.50) | PARP1 | |
| SCHEMBL358670 | 0.73 | PARP1 (0.52) | PARP1 | |
| SCHEMBL358920 | 0.72 | NR3C1 (0.43) | PARP1 | |
| SCHEMBL359228 | 0.72 | PARP1 (0.48) | PARP1 | |
| SCHEMBL359589 | 0.71 | RPS6KB1 (0.49) | PARP1 | |
| SCHEMBL359223 | 0.71 | PARP1 (0.49) | PARP1 | |
| SCHEMBL357957 | 0.71 | PARP1 (0.44) | PARP1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006958-A1 | AMIDS SUBSTITUTED INDAZOLE DERIVATIVEES AS PLOY(ADP-RIBOSE)POLYMERASE INHIBITORS | ZHEJIANG BETA PHARMA INC. (CN) | 2012-01-19 | — | — | WO | disclosed |