Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13031176 | 0.92 | HTT (0.38) | GAAHTTHDAC1HDAC7CYP1A2 | |
| SCHEMBL3588862 | 0.79 | ENPP2 (0.36) | GAAHDAC1HDAC7KMT2AKDM4E | |
| SCHEMBL3588863 | 0.76 | ENPP2 (0.34) | GAAHDAC1HDAC7CYP1A2CYP2C19 | |
| SCHEMBL11832142 | 0.70 | HTT (0.46) | GAAHTTL3MBTL1EPHX2KDM4E | |
| SCHEMBL23174789 | 0.70 | LMNA (0.43) | GAAHTTAGBL2EPHX2KDM4E | |
| SCHEMBL17151558 | 0.68 | ALDH1A1 (0.40) | GAAHTTCYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL28759029 | 0.65 | CYP4F2 (0.41) | GAAHDAC1KDM4E | |
| SCHEMBL13807673 | 0.65 | ALDH1A1 (0.56) | GAAHTTCYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL13031346 | 0.64 | CSNK2A2 (0.41) | GAAKDM4ESMN1; SMN2LMNAMAPT | |
| Trifluoroacetic Acid SCHEMBL27623336 | 0.64 | CES1 (0.56) | L3MBTL1KMT2AKDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | CXCR3, CXCR1, CXCR2 | GAA 4433/4885HTT 3557/4885HDAC1 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.