Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577970 | 0.93 | KIF11 (0.46) | KIF11METAP2ACE | |
| SCHEMBL3577967 | 0.93 | KIF11 (0.46) | KIF11METAP2ACE | |
| SCHEMBL357189 | 0.80 | ALPI (0.51) | CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL6895415 | 0.79 | ALPI (0.50) | CYP3A4TSHR | |
| SCHEMBL1653274 | 0.79 | METAP2 (0.49) | METAP2ACE | |
| SCHEMBL3592883 | 0.78 | ACE (0.47) | METAP2ACE | |
| SCHEMBL3575636 | 0.77 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL12888845 | 0.76 | ALDH1A1 (0.51) | METAP2CYP3A4ACE | |
| SCHEMBL7544294 | 0.74 | CTSC (0.51) | METAP2ACE | |
| SCHEMBL3503447 | 0.73 | GLO1 (0.53) | METAP2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048549-A1 | Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 | Wurster, Siegfried (FI) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048549-A1 | Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 | SSTR1, SSTR4, SSTR3 | KIF11 2691/4885CCR2 1466/4885OPRK1 878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.