Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | CA3 | P07451 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | CA4 | P22748 | 1/20 | 0.66 |
| ▸ | CA6 | P23280 | 1/20 | 0.66 |
| ▸ | CA5A | P35218 | 1/20 | 0.66 |
| ▸ | CA7 | P43166 | 1/20 | 0.66 |
| ▸ | CA9 | Q16790 | 1/20 | 0.66 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.66 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.66 |
| ▸ | TPMT | P51580 | 2/20 | 0.63 |
| ▸ | TTR | P02766 | 2/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | JUN | P05412 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31447584 | 1.00 | CA12 (0.66) | CA12CA1CA2CA3PKM | |
| SCHEMBL8728260 | 0.88 | TTR (0.60) | CA12CA1CA2CA3PKM | |
| SCHEMBL7371831 | 0.88 | TTR (0.60) | CA12CA1CA2CA3PKM | |
| SCHEMBL31059025 | 0.87 | LMNA (0.66) | CA12CA1CA2CA3PKM | |
| SCHEMBL5598228 | 0.87 | LMNA (0.66) | CA12CA1CA2CA3PKM | |
| SCHEMBL31059024 | 0.87 | LMNA (0.66) | CA12CA1CA2CA3PKM | |
| SCHEMBL15018739 | 0.86 | TTR (0.61) | CA12CA1CA2CA3PKM | |
| SCHEMBL31290239 | 0.86 | TTR (0.61) | CA12CA1CA2CA3PKM | |
| SCHEMBL750055 | 0.86 | TTR (0.61) | TPMTTTRJUNMAPTSMN1; SMN2 | |
| SCHEMBL1447399 | 0.85 | TPMT (0.74) | CA12CA1CA2CA3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504444-A | Preparation method of 5-nitrovanillic acid | 浙江工业大学 | 2025-02-25 | — | — | CN | claimed |
| CN-112375014-A | Oppicapone process impurity, preparation method and application | 重庆柳江医药科技有限公司 | 2021-02-19 | — | — | CN | claimed |
| WO-2014147464-A2 | NOVEL PROCESS FOR THE PREPARATION OF TOLCAPONE | RA CHEM PHARMA LIMITED (IN) | 2014-09-25 | — | — | WO | claimed |
| EP-4727649-A1 | PROCESS FOR PREPARING OPICAPONE | Medichem, S.A. (ES) | 2026-04-22 | — | — | EP | disclosed |
| US-20260035341-A1 | FTO INHIBITORS | RPXDS CO LTD (CN) | 2026-02-05 | — | — | US | disclosed |
| EP-4638412-A1 | PROCESSES AND INTERMEDIATES FOR SYNTHESISING OPICAPONE | BIAL - Portela & Ca., S.A. (PT) | 2025-10-29 | — | — | EP | disclosed |
| US-20250263384-A9 | REDOX-ACTIVE COMPOUNDS AND USES THEREOF | CMBLU ENERGY AG (DE) | 2025-08-21 | — | — | US | disclosed |
| EP-4561975-A1 | FTO INHIBITORS | RPXDS Co., Ltd (CN) | 2025-06-04 | — | — | EP | disclosed |
| CN-119546566-A | FTO inhibitors | 瑞璞鑫(苏州)生物科技有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119504444-A | Preparation method of 5-nitrovanillic acid | 浙江工业大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-119504444-A | Preparation method of 5-nitrovanillic acid | 浙江工业大学 | 2025-02-25 | — | — | CN | disclosed |
| US-20070142399-A1 | Dual function drugs and uses thereof | PSYCHIATRIC GENOMICS, INC. (US) | 2007-06-21 | — | — | US | disclosed |
| US-5705703-A | ENZYME INHIBITORS OF TRANSFERASES | HOFFMANN-LA ROCHE INC. (US) | 1998-01-06 | — | — | US | disclosed |
| US-5633371-A | ENZYME INHIBITORS; TREATMENT OF DEPRESSION AND PARKINSON*S DISEASE | HOFFMANN-LA ROCHE INC. (US) | 1997-05-27 | — | — | US | disclosed |
| US-5476875-A | Catechol derivatives | HOFFMAN-LA ROCHE INC. (US) | 1995-12-19 | — | — | US | disclosed |
| US-5389653-A | Inhibitors of the enzyme catechol-O-methyltransferase; useful as co-medication in treatment of Parkinson's disease | HOFFMAN-LA ROCHE INC. (US) | 1995-02-14 | — | — | US | disclosed |
| US-5236952-A | Inhibit the enzyme catechol-O-methyltransferase; for treatment of Parkinson's disease administered with L-dopa | HOFFMANN-LA ROCHE INC. (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0237929-B1 | 3,5-DISUBSTITUTED PYROCATECHOL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-02 | — | — | EP | disclosed |
| EP-0237929-A1 | 3,5-Disubstituted pyrocatechol derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1987-09-23 | — | — | EP | disclosed |
| US-4377490-A | CYANOACRYLATE, ETHERS, ALCOHOLS, ACIDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | FTO, LDLR, GPR119 | CA12 4386/4885CA1 3210/4885CA2 3929/4885 |
| US-20250263384-A9 | REDOX-ACTIVE COMPOUNDS AND USES THEREOF | NOX4, NQO1, GPX1 | CA12 1993/4885CA1 1806/4885CA2 1635/4885 |
| US-20070142399-A1 | Dual function drugs and uses thereof | COMT, DRD2, SLC6A3 | CA12 4147/4885CA1 2533/4885CA2 3784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.