Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 6/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 6/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | CENPE | Q02224 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3574238 | 0.92 | MLYCD (0.35) | HSP90AA1MLYCDCENPESIGMAR1OPRM1 | |
| SCHEMBL3584126 | 0.91 | ESRRG (0.36) | GBA1HSP90AA1SSTR2SSTR4SIGMAR1 | |
| SCHEMBL3569329 | 0.84 | C5AR1 (0.41) | MLYCD | |
| SCHEMBL3576692 | 0.83 | ESRRG (0.37) | HSP90AA1SIGMAR1OPRM1OPRD1TRPV1 | |
| SCHEMBL3580029 | 0.83 | MLYCD (0.34) | HSP90AA1MLYCDCENPESIGMAR1OPRM1 | |
| SCHEMBL3579477 | 0.82 | MCHR1 (0.37) | MLYCD | |
| SCHEMBL3578672 | 0.82 | GBA1 (0.34) | GBA1HSP90AA1SSTR2SSTR4SIGMAR1 | |
| SCHEMBL3575573 | 0.82 | HSP90AA1 (0.36) | GBA1HSP90AA1SSTR2SSTR4OPRM1 | |
| SCHEMBL3574285 | 0.82 | ESRRG (0.36) | HSP90AA1CENPESIGMAR1OPRM1OPRD1 | |
| SCHEMBL3581186 | 0.81 | CNR1 (0.39) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-2654751-A1 | PHOSPHORUS-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF | Purdue Pharma L.P. (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012085648-A9 | PHOSPHORUS-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF | PURDUE PHARMA L.P. (US) | 2013-03-21 | — | — | WO | disclosed |
| WO-2012085648-A1 | PHOSPHORUS-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF | PURDUE PHARMA L.P. (US) | 2012-06-28 | — | — | WO | disclosed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |