Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPD | P32754 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634693 | 0.93 | MAPT (0.40) | MAPTCA12CA1CA2CA9 | |
| Trifluoroacetic Acid SCHEMBL3572326 | 0.84 | TYMS (0.39) | MAPTCA1CA2ALDH1A1CYP3A4 | |
| SCHEMBL3572332 | 0.83 | CYP3A4 (0.33) | MAPTALDH1A1ABCB1POLBHPD | |
| SCHEMBL3574966 | 0.82 | ITGA4 (0.35) | MAPTALDH1A1POLBCYP3A4ALOX15 | |
| SCHEMBL3574028 | 0.78 | ALDH1A1 (0.40) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL3586516 | 0.77 | ALDH1A1 (0.40) | MAPTCA1CA2ALDH1A1CYP3A4 | |
| SCHEMBL3569098 | 0.69 | ALDH1A1 (0.39) | MAPTALDH1A1ABCB1TDP1LMNA | |
| SCHEMBL28736276 | 0.66 | ALDH1A1 (0.44) | MAPTALDH1A1POLBCYP3A4ALOX15 | |
| SCHEMBL616603 | 0.65 | GAA (0.63) | MAPTALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL19699034 | 0.65 | L3MBTL1 (0.53) | MAPTALDH1A1TDP1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771368-B2 | 18F-labelled folates | Merck & Cie (CH) | 2017-09-26 | — | — | US | disclosed |
| US-20160159802-A1 | 18F-LABELLED FOLATES | Merck & Cie (CH) | 2016-06-09 | — | — | US | disclosed |
| US-9315506-B2 | 18F-labelled folates | Merck & Cie (CH) | 2016-04-19 | — | — | US | disclosed |
| US-20100056533-A1 | 18F-LABELLED FOLATES | MERCK EPROVA AG (CH) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056533-A1 | 18F-LABELLED FOLATES | FOLR1, FOLR2, SLC19A1 | MAPT 2880/4885CA12 1260/4885CA1 1904/4885 |
| US-20160159802-A1 | 18F-LABELLED FOLATES | FOLR1, FOLR2, SLC19A1 | MAPT 2805/4885CA12 1057/4885CA1 1735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.