Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 4/20 | 0.36 |
| ▸ | GABRD | O14764 | 4/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.36 |
| ▸ | GABRE | P78334 | 4/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29505054 | 0.74 | ALDH1A1 (0.39) | ALDH1A1MEN1MAPTKMT2AMAPK1 | |
| SCHEMBL3575369 | 0.69 | MAPT (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19411262 | 0.68 | AHR (0.44) | KDM4EGAA | |
| SCHEMBL571799 | 0.67 | MAPK1 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9270824 | 0.66 | PDE4B (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17430598 | 0.65 | ALDH1A1 (0.44) | ALDH1A1TSHRTNKSMEN1MAPT | |
| SCHEMBL571569 | 0.65 | MEN1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3576396 | 0.65 | GABRA1 (0.34) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL19269464 | 0.64 | ALDH1A1 (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL854628 | 0.64 | TGM2 (0.38) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022526-A1 | PYRIDAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-01-28 | — | — | US | disclosed |
| EP-2121628-A1 | PYRIDAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | Syngenta Participations AG (CH) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008089934-A1 | PYRIDAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022526-A1 | PYRIDAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | CYP4Z1, CYP1A2, CYP1A1 | GABRP 2236/4885GABRD 2735/4885GABRA1 820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.