Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Isobutyl Ketone SCHEMBL28689973 | 0.95 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRCA2LMNA | |
| Methyl Isobutyl Ketone SCHEMBL105947 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TDP1TSHRCA2LMNA | |
| Methyl Isobutyl Ketone SCHEMBL139429 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TDP1TSHRCA2LMNA | |
| Methyl Isobutyl Ketone SCHEMBL15458 | 0.84 | — | — | |
| Methyl Isobutyl Ketone SCHEMBL1580340 | 0.84 | — | — | |
| Methyl Isobutyl Ketone SCHEMBL1128055 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TDP1CA2MMP1MMP2 | |
| Ether SCHEMBL28945221 | 0.82 | CYP2C19 (0.46) | ALDH1A1TDP1TSHRCA2LMNA | |
| Methyl Isobutyl Ketone SCHEMBL10817055 | 0.82 | ALDH1A1 (0.70) | ALDH1A1TDP1TSHRLMNAHSD17B10 | |
| Methyl Isobutyl Ketone SCHEMBL306141 | 0.81 | ALDH1A1 (0.82) | ALDH1A1TDP1CA2CYP2C19 | |
| Methyl Isobutyl Ketone SCHEMBL9056069 | 0.81 | ALDH1A1 (0.82) | ALDH1A1TDP1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060318-A2 | POLYMORPHIC FORMS OF RAMELTEON AND PROCESSES FOR PREPARATION THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-05-14 | — | — | WO | claimed |
| US-20090105490-A1 | Polymorphic forms of ramelteon and processes for preparation thereof | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-04-23 | — | — | US | claimed |
| US-11958805-B2 | Solid forms comprising an oxime ether compound, compositions and methods of use thereof | NOVARTIS AG (CH) | 2024-04-16 | — | — | US | disclosed |
| CN-116425981-A | Metal/metalloid-containing polymers and methods of making and using same | 上海邃铸科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-108794342-B | Ammonium carboxylate compound, crystal form and amorphous form thereof and preparation method thereof | 武汉朗来科技发展有限公司 | 2023-04-14 | — | — | CN | disclosed |
| EP-3611160-B1 | AMMONIUM CARBOXYLATE COMPOUND, CRYSTAL FORM AND AMORPHOUS SUBSTANCE THEREOF, AND PREPARATION METHOD THEREFOR | WUHAN LL SCIENCE & TECHNOLOGY DEVELOPMENT CO LTD (CN) | 2023-03-29 | — | — | EP | disclosed |
| US-11161803-B2 | Ammonium carboxylate compound, crystalline form, amorphous form and preparation method thereof | WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2021-11-02 | — | — | US | disclosed |
| CN-109219607-B | Crystalline forms of succinate salt of dipeptidyl peptidase-IV inhibitor | 吉林惠升生物制药有限公司 | 2021-03-30 | — | — | CN | disclosed |
| US-20200377454-A1 | Solid Forms Comprising An Oxime Ether Compound, Compositions and Methods of Use Thereof | NOVARTIS INTERNATIONAL PHARMACEUTICAL AG (CH) | 2020-12-03 | — | — | US | disclosed |
| US-20200055812-A1 | AMMONIUM CARBOXYLATE COMPOUND, CRYSTALLINE FORM, AMORPHOUS FORM AND PREPARATION METHOD THEREOF | WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2020-02-20 | — | — | US | disclosed |
| EP-3611160-A1 | AMMONIUM CARBOXYLATE COMPOUND, CRYSTAL FORM AND AMORPHOUS SUBSTANCE THEREOF, AND PREPARATION METHOD THEREFOR | Wuhan LL Science And Technology Development Co., Ltd. (CN) | 2020-02-19 | — | — | EP | disclosed |
| EP-2415594-A1 | DECORATIVE MEMBER | Fujikura, Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120015180-A1 | DECORATIVE MEMBER | FUJIKURA LTD. (JP) | 2012-01-19 | — | — | US | disclosed |
| EP-2064067-A1 | INK, INK CARTRIDGE, INK JET RECORDING APPARATUS, AND INK JET RECORDING METHOD | Ricoh Company, Ltd. (JP) | 2009-06-03 | — | — | EP | disclosed |
| WO-2009060318-A2 | POLYMORPHIC FORMS OF RAMELTEON AND PROCESSES FOR PREPARATION THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-05-14 | — | — | WO | disclosed |
| US-20090105490-A1 | Polymorphic forms of ramelteon and processes for preparation thereof | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-04-23 | — | — | US | disclosed |
| WO-2008035797-A1 | INK, INK CARTRIDGE, INK JET RECORDING APPARATUS, AND INK JET RECORDING METHOD | RICOH COMPANY, LTD. (JP) | 2008-03-27 | — | — | WO | disclosed |
| US-20070293514-A1 | Triazolopyrimidines | BAYER CROPSCIEMCE AG (DE) | 2007-12-20 | — | — | US | disclosed |
| CN-101044123-A | Pyrimidine derivatives condensed with non-aromatic rings | ASTELLAS PHARMA INC (JP) | 2007-09-26 | — | — | CN | disclosed |
| US-4098844-A | ADDITION COPOLYMER STABILIZED WITH AN ISOCYANATE-CONTAINING POLYMER | DAI NIPPON TORYO CO., LTD. (JP) | 1978-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11958805-B2 | Solid forms comprising an oxime ether compound, compositions and methods of use thereof | CYP2E1, CYP2C9, CYP3A43 | ALDH1A1 343/4885TDP1 2405/4885TSHR 1946/4885 |
| US-20200377454-A1 | Solid Forms Comprising An Oxime Ether Compound, Compositions and Methods of Use Thereof | CYP2E1, CYP2C9, CYP3A43 | ALDH1A1 343/4885TDP1 2405/4885TSHR 1946/4885 |
| US-20090105490-A1 | Polymorphic forms of ramelteon and processes for preparation thereof | CYP2D6, CYP2B6, CYP3A43 | ALDH1A1 2850/4885TDP1 1162/4885TSHR 3061/4885 |
| US-20070293514-A1 | Triazolopyrimidines | QDPR, DPYD, Q6ZSR9 | ALDH1A1 1155/4885TDP1 55/4885TSHR 1273/4885 |
| US-11161803-B2 | Ammonium carboxylate compound, crystalline form, amorphous form and preparation method thereof | ACMSD, ADSL, AMD1 | ALDH1A1 1026/4885TDP1 2339/4885TSHR 4422/4885 |
| US-20200055812-A1 | AMMONIUM CARBOXYLATE COMPOUND, CRYSTALLINE FORM, AMORPHOUS FORM AND PREPARATION METHOD THEREOF | ACMSD, ADSL, AMD1 | ALDH1A1 1026/4885TDP1 2339/4885TSHR 4422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.