Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | LTK | P29376 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | MST1R | Q04912 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358604 | 0.73 | HTR1A (0.50) | HTR1AHTR7TRPV1 | |
| SCHEMBL972896 | 0.71 | KDR (0.54) | HTR1AHTR7LTKCDK5MST1R | |
| SCHEMBL3687337 | 0.71 | LTK (0.49) | HTR1AHTR7LTKCDK5MST1R | |
| SCHEMBL11077815 | 0.70 | HTR1A (0.50) | HTR1AHTR7LTKCDK5MST1R | |
| SCHEMBL5952956 | 0.67 | ACHE (0.57) | HTR1AHTR7LTKCDK5MST1R | |
| SCHEMBL28809874 | 0.67 | LTK (0.48) | HTR1AHTR7LTKCDK5MST1R | |
| SCHEMBL287202 | 0.66 | SLC18A3 (0.48) | TRPV1 | |
| SCHEMBL13091093 | 0.66 | ACHE (0.39) | ALDH1A1TRPV1 | |
| SCHEMBL12540413 | 0.66 | SLC18A3 (0.48) | TRPV1 | |
| SCHEMBL9455952 | 0.66 | TRPV1 (0.38) | CDK5DYRK1ACLK4DRD2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741511-B2 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-22 | — | — | US | claimed |
| US-20080009648-A1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS | SOUDA HIROSHI | 2008-01-10 | — | — | US | claimed |
| EP-1792889-A2 | Process for the preparation of carboxylic acid esters | Sumitomo Chemical Company, Limited (JP) | 2007-06-06 | — | — | EP | claimed |
| EP-1547995-A1 | Process for the preparation of carboxylic acid esters | Sumitomo Chemical Company, Limited (JP) | 2005-06-29 | — | — | EP | claimed |
| US-20050113581-A1 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL COMPANY, LIMITED | 2005-05-26 | — | — | US | claimed |
| EP-1547995-B1 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL CO (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-2418197-B1 | PROCESS FOR PRODUCING 3-(2-CYANO-1-PROPENYL)-2,2- DIMETHYLCYCLOPROPANECARBOXYLIC ACID OR SALT THEREOF | SUMITOMO CHEMICAL CO (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-8461370-B2 | Process for producing 3-(2-cyano-1-propenyl)-2,2- dimethylcyclopropanecarboxylic acid or salt thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-11 | — | — | US | disclosed |
| EP-2537828-A1 | METHOD FOR PRODUCING CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID SALT | Sumitomo Chemical Company, Limited (JP) | 2012-12-26 | — | — | EP | disclosed |
| US-20120310003-A1 | METHOD FOR PRODUCING CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID SALT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-06 | — | — | US | disclosed |
| EP-2418197-A1 | PROCESS FOR PRODUCING 3-(2-CYANO-1-PROPENYL)-2,2- DIMETHYLCYCLOPROPANECARBOXYLIC ACID OR SALT THEREOF | Sumitomo Chemical Company, Limited (JP) | 2012-02-15 | — | — | EP | disclosed |
| US-20120016150-A1 | Process for Producing 3-(2-Cyano-1-propenyl)-2,2- Dimethylcyclopropanecarboxylic Acid or Salt Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-19 | — | — | US | disclosed |
| CN-1354166-A | Process for preparing cyclopropane carboxylic acid ester | SUMITOMO CHEMICAL CO (JP) | 2002-06-19 | — | — | CN | disclosed |
| EP-1203760-A1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-08 | — | — | EP | disclosed |
| US-20020052525-A1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-02 | — | — | US | disclosed |
| EP-1061065-A2 | Methods for producing cyclopropane carboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-12-20 | — | — | EP | disclosed |
| EP-0992479-A1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-4442296-A | LARVICIDES | FMC CORPORATION (US) | 1984-04-10 | — | — | US | disclosed |
| US-4408057-A | 4-Heterocyclic-substituted-2-indanyl alcohols and insecticidal ester derivatives | FMC CORPORATION (US) | 1983-10-04 | — | — | US | disclosed |
| US-4368205-A | 4-Heterocyclic-substituted-2-indanyl alcohols and insecticidal ester derivatives | FMC CORPORATION (US) | 1983-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113581-A1 | Process for the preparation of carboxylic acid esters | ACSL6, ALKBH3, ACSL1 | HTR1A 2624/4885HTR7 1969/4885LTK 983/4885 |
| US-20120310003-A1 | METHOD FOR PRODUCING CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID SALT | MCCC2, AOC2, DDC | HTR1A 1643/4885HTR7 1438/4885LTK 4450/4885 |
| US-20020052525-A1 | Method for producing cyclopropanecarboxylates | CYP8B1, SRD5A2, CYP21A2 | HTR1A 854/4885HTR7 330/4885LTK 4299/4885 |
| US-20120016150-A1 | Process for Producing 3-(2-Cyano-1-propenyl)-2,2- Dimethylcyclopropanecarboxylic Acid or Salt Thereof | CPS1, PCCA, PKD1 | HTR1A 2848/4885HTR7 3708/4885LTK 4651/4885 |
| US-20080009648-A1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS | ACSL6, ALKBH3, ACSL1 | HTR1A 2624/4885HTR7 1969/4885LTK 983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.